Small question on peptide bond

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shobber
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Small question on peptide bond

Post by shobber » Wed Jun 04, 2008 3:39 pm

Hi all, I have a question on the peptide bond. Stryers Biochemistry says that "peptide bonds are quite stable kinetically", but I don't know what stable kinetically means.

Can anyone explain it? Thanks in advance.

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jonmoulton
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Re: Small question on peptide bond

Post by jonmoulton » Wed Jun 04, 2008 4:53 pm

The bond has a high activation energy for hydrolysis, so without catalysis it is unlikely to react at room temperature. That is what is meant by "stable kinetically".

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Re: Small question on peptide bond

Post by shobber » Thu Jun 05, 2008 3:30 pm

Thanks a lot!

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