Hutchinson-Gilford Progeria Syndrome

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Hutchinson-Gilford Progeria Syndrome

Post by Rukesh » Tue May 13, 2008 7:44 am

Can anyone help me out where i can find latest news or developments on HGPS ????

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Re: Hutchinson-Gilford Progeria Syndrome

Post by jonmoulton » Wed May 21, 2008 8:39 pm

Here are a few references describing research into HGPG using cell culture studies and oligo-based redirection of the splicing of lamin-A.

Scaffidi P, Misteli T. Lamin A-dependent nuclear defects in human aging. Science. 2006 May 19;312(5776):1059-63. Epub 2006 Apr 27.

Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med. 2005 Apr;11(4):440-5. Epub 2005 Mar 6.

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