Tetrazolium

Discussion of all aspects of cellular structure, physiology and communication.

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HoistDaColors
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Tetrazolium

Post by HoistDaColors » Sun Mar 30, 2008 2:33 am

Does anyone know how tetrazolium cross the membrane to the matrix of the mitochondria? Can I expect that it is hydrophobic enough to diffuse through the membrane? It is a chemical that changes color when reduced. The enzyme responsible is succinate dehydrogenase (oxidizing NADH). Everywhere says that it is a salt. When you look at the structure, there are three phenyl groups hiding the positive charge. Can that be enough to diffuse through the membrane? I highly doubt there is a specific transporter for it.

Thanks in advance.

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