Serum IgM cannot activate the complement?

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vaibhavsmarty
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Serum IgM cannot activate the complement?

Post by vaibhavsmarty » Sat Feb 16, 2008 5:21 am

why??????????
four possibilities can be:
a/it does not have complement binding site
b/it is planar in which complement binding sites in the Fc region are not accesible
c/it gets degraded and hence unable to activate the complement
d/it needs metal ions to activate complement
PLZ HELP!!!!!!!!!!!
VaIbHaV tYaGi
where ways seem to be converging call the almighty

preechaedu
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Re: Serum IgM cannot activate the complement?

Post by preechaedu » Sat Jun 23, 2012 11:15 am

b is correct.

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