Gene order

Genetics as it applies to evolution, molecular biology, and medical aspects.

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biology_06er
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Gene order

Post by biology_06er » Sat Sep 08, 2007 9:56 am

Hey there,

Just wondering about how to deduce gener order by inspecting parental and double xovers..

the example in book is...parentals=v.cv+.ct+ and v+.cv.ct
and the double xovers=v.cv+.cv and v+.cv.ct+

i get how to draw the linkage map but don't get how you can find out the order (which the ans. is v.ct.ctv..ive jsut read 2 textbooks on it and still confused :-(...

someone please help!

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MrMistery
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Post by MrMistery » Sat Sep 08, 2007 6:20 pm

if you have a linkage map don't you have the order? a linkage map conserves gene order, it just doesn't conserve distance between genes
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Post by biology_06er » Wed Sep 12, 2007 9:18 am

you sure?

because in my book (both books) it says that you can just deduce the gener order by looking at the data??

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Post by MrMistery » Thu Sep 13, 2007 5:50 am

well, do you know what a linkage map is? It's genes in order on a chromosome, disregarding distance between them. So you see, it's really kinda the same thing
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Post by biology_06er » Thu Sep 13, 2007 6:17 am

yes I know what one is, but say all you have data wise is the following:

parentals=+++ and abc
double xovers=+bc and a++

how can I work out the gene order??

Get what I mean?

Thanks,
b_06er

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MrMistery
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Post by MrMistery » Thu Sep 13, 2007 8:56 am

you can't. you need frequencies. otherwise you can't tell anything
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Post by biology_06er » Fri Sep 14, 2007 12:09 pm

you probably misundetstood my question because you can find the gene order just by looking at the data in my last post--my friend explained it to me...cos theres only 3 gene orders possible with a different allele in the middle) then you cross them and see which one ends up as the double xova...

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