Theoretical biologists developing a protein folding theory?

Punita · Post by **Punita** » Mon Jul 16, 2007 6:51 pm

Theoretical biologists developing a protein folding theory?

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Post by Punita » Mon Jul 16, 2007 6:51 pm

Hi, I wondered if anybody knew whether there are any purely theoretical biologists working on developing a theory of protein folding? Any names would be great! Thanks!

victor · Post by **victor** » Tue Jul 17, 2007 4:14 am

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Post by victor » Tue Jul 17, 2007 4:14 am

the folding of protein happens in 3 ways, (1) it folds by itself, (2) helped by proteins named chaperones, and (3) helped by a large dome-like protein chaperonins.

for the no.1, it can fold to a proper structure sometimes because of series of actions happened after translation, called post-translational modification, like amino-acid modification. But the major factor that affects the proper folding is that the sequence of each amino-acid in the protein itself

Q: Why are chemists great for solving problems?
A: They have all the solutions.

blcr11 · Post by **blcr11** » Tue Jul 17, 2007 11:31 am

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Post by blcr11 » Tue Jul 17, 2007 11:31 am

There should be lots of labs doing this kind of theoretical work--Ken Dill's lab comes to mind (at one of the California universities--I forget which off-hand). Go to PubMed and search for theory protein folding or something similar, then open the reviews tab. You should get lots of possibilities. Open the citation and there should also be at least one contact e-mail or address.