erythroblastosis fetalis

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Poison
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Post by Poison » Sun Jul 10, 2005 6:35 pm

I don't think it can.
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Post by victor » Tue Jul 12, 2005 11:27 am

Hey Ozge, I've checked my book and I found it...yes, it's true that only IgG can pass through placenta. The others (IgA, IgM, IgD, IgE) can't pass. But IgM can be formed as the primary immune response.
IgA is the main immunoglobulin from secrets such as saliva, milk, etc...it protects the mukosa from bacterias and viruses.
IgE act as the fast response allergic because it's contained in basophyll
IgD act as the certain antigen response...majority contained in B limphocyte.
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Post by chemistry_freako » Tue Jul 12, 2005 3:32 pm

hmms...why is it that only IgG can pass through?
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Post by Poison » Tue Jul 12, 2005 4:42 pm

small molecular weight.
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Post by victor » Thu Jul 14, 2005 12:34 pm

I think its MW (molecular weight) is 400.000 AMQ (atom mass quantity)
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Post by Poison » Thu Jul 14, 2005 3:03 pm

It says that:
IgA :160,000* (Looks small too but it aggregates with higher molecular weights)
IgM: 900,000*
IgG: 150,000*
IgE: 200,000*
IgD: 185,000*

*: Daltons approximately
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Post by victor » Sat Jul 16, 2005 12:37 pm

IgA gets in together with milk from their mom..so, no need placenta then.. :lol:
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Post by Poison » Sat Jul 16, 2005 12:53 pm

Yeah. But I haven't seen a mother suckling a fetus. :lol:
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Post by victor » Sat Jul 16, 2005 12:58 pm

Maybe after this diagram:
Embryo - fetus - [born] - baby

That's when they get the IgA.. :lol:
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Post by Poison » Sat Jul 16, 2005 1:08 pm

Good diagram. ;)
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Post by 2810712 » Tue Jul 19, 2005 8:52 am

What is the mechanism for IgG to get into the fetus?
Probably it is forced into the blood of fetus though the fenistrations in the maternal capillaries , so the size , shape and molecular wt. all matter.

M I RIGHT???

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Post by victor » Tue Jul 19, 2005 11:47 am

Or maybe they can be carried out through endocytocys and exocytocys....
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