DNA degradation

Debate and discussion of any biological questions not pertaining to a particular topic.

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kalpanarajan
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DNA degradation

Post by kalpanarajan » Fri Jun 01, 2007 5:05 am

Hellow

This is Kalpana, recently i have joined in this group. I would like to know the Human DNA Degradation by Biochemical, Bacterial and Oxidation process.
What actually happens in these process and how DNA getting degradtion by these process?

Thank you

david23
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Post by david23 » Fri Jun 01, 2007 6:07 am

in living cells its usually degraded by different types of nucleases. DNA breaks down into individual nucleotides.

pez123
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Hmmm

Post by pez123 » Fri Jun 01, 2007 7:51 am

I would say damage to the chemical structure of the DNA such as oxidative stress brought upon by the oxidation of nucleotide positions. In terms of bacterial I am not sure... I mean... They have DNA so they are subjected to the same mutagenizing processes. They dont usualy cause DNA damage, or I have not heard of a tumor inducing bacterial pathogen before.

david23
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Post by david23 » Fri Jun 01, 2007 2:04 pm

oxidative stress that induce the apoptosis pathway will eventually activate nucleases.

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