Bioinformatics - DNA sequencing

Everything on bioinformatics, the science of information technology as applied to biological research.

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TToe
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Bioinformatics - DNA sequencing

Post by TToe » Wed Dec 05, 2012 4:01 am

Take a look at the DNA alignment of two genes:

http://www.ebi.ac.uk/Tools/services/res ... 408-pg/aln


The Homo Sapien is the longest DNA sequence. If the Homo Sapien gene has 1770 bases surely the overall aligned length should also be 1770, so why is it 1899?

Also what exactly does the dots in the diagram represent?

TToe
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Post by TToe » Wed Dec 05, 2012 4:45 am

I get it, I didn't count the gaps.

What do the dots in the diagram represent?

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JackBean
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Post by JackBean » Wed Dec 05, 2012 4:56 pm

yes, gaps are that

the dots mark mutations (different nucleotides)
http://www.biolib.cz/en/main/

Cis or trans? That's what matters.

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