Mendelian vs. Multifactorial

Genetics as it applies to evolution, molecular biology, and medical aspects.

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Mendelian vs. Multifactorial

Post by merced12 » Fri Oct 13, 2006 4:52 am

I'm trying to write up a report on mendelian disorders. So I picked Thromobophilia. Thromobophilia is a multifactorial trait. According to OMIM (Online Mendelian Inheritance of Man),

"Thrombophilia is a complex (multifactorial) trait. The genes involved in complex traits are, for the most part, susceptibility genes, not genes that represent the primary cause of the disorder, as in the case of mendelian disorders. "

Therefore, will this count as a Mendelian disorder?

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Post by MrMistery » Fri Oct 13, 2006 10:06 am

if you define a mendelian disorder as a disorder transmitted according to mendelian laws, deffinetly not!
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter

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