hox, homeotic, homeobox

Genetics as it applies to evolution, molecular biology, and medical aspects.

Moderators: honeev, Leonid, amiradm, BioTeam

Post Reply
biologygeek83
Garter
Garter
Posts: 3
Joined: Tue Oct 03, 2017 1:12 am

hox, homeotic, homeobox

Post by biologygeek83 » Tue Oct 03, 2017 1:30 am

do these terms refer to the same thing? i thought so from the reading i've done, but wikipedia contradicts this.

biologygeek83
Garter
Garter
Posts: 3
Joined: Tue Oct 03, 2017 1:12 am

Post by biologygeek83 » Wed Oct 04, 2017 3:54 am

this is what i've found from further reading:

homeotic genes control the body plan.
homeotic genes in organisms which display bilateral symmetry (including vertebrates ) are called Hox genes.

some genes contain a highly conserved sequence of 180bp, leading to the synthesis of a 60aa polypeptide. this conserved sequence is called the homeobox and the 60aa polypeptide is the homeodomain. it forms (part of) a transcription factor.

the homeobox is found in Hox genes. however, there are other homeobox-containing genes that are not Hox genes, which regulate expression of areas other than the body plan.

Post Reply

Who is online

Users browsing this forum: No registered users and 7 guests