Search found 215 matches

by zami'87.
Mon Feb 22, 2010 4:19 pm
Forum: Cell Biology
Topic: Human chromosomes
Replies: 16
Views: 10059

Re:

@jwalin

I think you should check this http://en.wikipedia.org/wiki/Pseudoautosomal_region
by zami'87.
Mon Feb 22, 2010 4:11 pm
Forum: Cell Biology
Topic: Why so few beta-sheet membrane proteins?
Replies: 3
Views: 4217

Re: Why so few beta-sheet membrane proteins?

As I remember alpha helices slide past others and they're more convenient for signal transduction or transport...beta barrels are rigid structures...
by zami'87.
Sat Jan 23, 2010 3:09 pm
Forum: Genetics
Topic: Human aging
Replies: 20
Views: 23936

Re: Human aging

Unfortunately I don't have time to read all posts right now but I read about regenerative capabilities of cells transplated from old to young mouse..It's more about factors from surrounding(ligands) as when such cells are transplated to young mouse they increase proliferation.Also some study in mice...
by zami'87.
Mon Jan 18, 2010 10:10 am
Forum: Molecular Biology
Topic: Difference between histone's and DNA's methyltransferase?
Replies: 3
Views: 2806

Re: Difference between histone's and DNA's methyltransferase?

I dunno if it helps..but you can detect DNA methylation by methylation specific PCR (MSP). First you treat DNA with sodium bisulfite under alkaline conditions.Result is conversion of unmethylated Cs to Us.Methylated Cs are unchanged.Then add specific primer that will anneal only if that segment of D...
by zami'87.
Mon Jan 18, 2010 9:10 am
Forum: Molecular Biology
Topic: molecular mechanism of inflammation
Replies: 9
Views: 9201

Re: molecular mechanism of inflammation

Maybe you could include cancer in that research as it has been discovered connection between inflammation and tumor promotion..there are plenty nice articles at NCBI...Good luck!
by zami'87.
Thu Dec 17, 2009 1:36 pm
Forum: Molecular Biology
Topic: Both rat and mouse as model organisms?
Replies: 6
Views: 2900

Re: Both rat and mouse as model organisms?

Mouse Genome Informatics Database
http://www.informatics.jax.org/
Rat Genome Database
http://rgd.mcw.edu/

Good luck with investigating!
by zami'87.
Thu Dec 17, 2009 12:42 pm
Forum: Molecular Biology
Topic: Ethidium
Replies: 5
Views: 5584

Re: Ethidium

Ethidium Bromide is intercalating agent.Intercalating agents can cause single nucleotide pair insertions/deletions and because of that frameshift mutations. Acrylamide is neurotoxin that destroys neurofilaments in axons and you can feel tingeling as skin absorbs it.. Here's also an article you may f...
by zami'87.
Tue Dec 15, 2009 11:18 am
Forum: General Discussion
Topic: Paralysing an eye
Replies: 4
Views: 1863

Re: Paralysing an eye

pupil widens(that's why eyes seem black),iris can't contract..for example because of oculomotor nerve damage.

http://en.wikipedia.org/wiki/Pupillary_light_reflex
by zami'87.
Tue Dec 15, 2009 5:35 am
Forum: Human Biology
Topic: No period, No sex, i don't know?
Replies: 14
Views: 14958

@jwalin, JackBean XY persons with Swyer syndrome have uterus(those with AIS don't have it) and with hormone therapy can bear pregnancy(donor of egg is necessary). Considering gender not sex-gonads there's Thomas Beatie's case..female to male transsexuals can be pregnant if they stop testosterone the...
by zami'87.
Thu Dec 10, 2009 5:09 am
Forum: Human Biology
Topic: No period, No sex, i don't know?
Replies: 14
Views: 14958

Re: No period, No sex, i don't know?

I'm not a doctor...Lack of menstruation can be due to anorexia because body saves energy( do you eat enough?)..next ovarian cysts could cause hormonal imbalance..You should do ultrasound, check hormones levels and (just in case) CA 125.. ps Talk to your mother and visit gynaecologist.Your parents ca...
by zami'87.
Sat Dec 05, 2009 5:06 pm
Forum: Human Biology
Topic: Cancer
Replies: 10
Views: 7153

Re: Cancer

Answer is no. Cause of cancer can be loss of function mutation that inhibits apoptosis(programmed cell death),or mutation that cause gain of function in mitogenic pathways so that cascade is activated even without proper signal. Sometimes there's defective receptor,G protein or other protein kinases...
by zami'87.
Sat Dec 05, 2009 3:10 am
Forum: Molecular Biology
Topic: Base Pair Geometries
Replies: 2
Views: 1657

Re: Base Pair Geometries

Check Understanding DNA by Calladine and Drew.They explain geometry of DNA and connect it with sequence..propeller twisted AA/TT with little roll and slide values(around 0 if you look plot) , GG/CC repel when slide is near zero(forbidden zone)..so they're moved(bistable on plot), CA/TG with wide ran...