Search found 74 matches

by kk
Tue Apr 17, 2018 8:12 pm
Forum: Cell Biology
Topic: Fermentation in the human body
Replies: 2
Views: 907

Re: Fermentation in the human body

I'm still keen to know more, please.
by kk
Thu Feb 15, 2018 7:50 pm
Forum: Genetics
Topic: What is the roan cattle and the Jappanese four o'clock ???
Replies: 3
Views: 4792

Re: What is the roan cattle and the Jappanese four o'clock ???

I thought roan meant two two hair colors are expressed simultaneously (e.g. black and white hair), instead of grey hair. But then I wouldn't understand, each heterozygous cell would grow multiple hairs? Just don't get it...
by kk
Mon Jan 29, 2018 10:27 am
Forum: Cell Biology
Topic: Fermentation in the human body
Replies: 2
Views: 907

Fermentation in the human body

I know that lactic acid fermentation is possible in muscle cells and mature red blood cells. My questions would be 1) all muscle cell types are able to perform lactic acid fermentation? 2) is there any other type of fermentation that a human cell (!) is able to perform in the body?
by kk
Sun Jan 28, 2018 3:23 pm
Forum: Cell Biology
Topic: Will we make more ATPs when inhaling pure oxygen?
Replies: 0
Views: 754

Will we make more ATPs when inhaling pure oxygen?

Will that boost ATP production in mitochondria? Or other reactions are rate limiting?
by kk
Fri Jan 26, 2018 9:54 am
Forum: Cell Biology
Topic: Where are enzymes in the smooth endoplasmic retuculum synthesized?
Replies: 0
Views: 716

Where are enzymes in the smooth endoplasmic retuculum synthesized?

Are they produced by RER-bound ribosomes or by free ribosomes and later they get imported into the SER. Also, how does the ER separate enzymes that work in the RER (e.g. glycosylases) from enzymes that work in the SER (e.g. detoxifying enzymes)? I know sometimes the ER is "mixed" so could be conside...
by kk
Wed Jul 27, 2016 8:54 am
Forum: Genetics
Topic: CpG methylation
Replies: 1
Views: 1992

CpG methylation

When people talk about DNA methylation at CpG sites, I keep seeing CpG spelled out as "cytosine-phosphorothioate-guanine"... isn't it all wrong? I thought CpG just means a cytosine and a guanine containing deoxyribonucleotide bonded with a normal phosphodiester bond, and "p" just...
by kk
Tue May 31, 2016 8:50 am
Forum: Molecular Biology
Topic: How to determine "zygosity" for a particular mutation?
Replies: 0
Views: 1428

How to determine "zygosity" for a particular mutation?

If two point (base substitution) mutations were detected adjacent to each other (by pyrosequencing), how do I know whether they were really next to each other in the same dsDNA molecule or one was present in the paternal dsDNA and the other in the maternal dsDNA?
by kk
Mon Nov 02, 2015 7:07 pm
Forum: Cell Biology
Topic: Exocytosis vs Pinocytosis
Replies: 2
Views: 8606

Question: once a cell secretes substances, can you only call it exocytosis? I mean, would there be sub-categories like secreting more liquid substances e.g. "cell sweating" as the reverse of pinocytosis "cell drinking"?
by kk
Mon Sep 08, 2014 2:57 pm
Forum: Cell Biology
Topic: mRNA vs. cell reporter assay
Replies: 3
Views: 7014

I have the same question, phrased in a slightly different way: Maybe the reporter system provides us with more information than RT-PCR/Western blot, because it proves that the transcription factor is actually active too, not just present? I thought it is enough to detect a significant increase in th...
by kk
Wed Aug 06, 2014 2:27 pm
Forum: Cell Biology
Topic: How did endosymbionts coordinate replication?
Replies: 12
Views: 23559

Fun study to read about, thanks for posting.
by kk
Thu Jul 10, 2014 2:45 pm
Forum: Molecular Biology
Topic: microsatellite instability
Replies: 3
Views: 5226

Re: microsatellite instability

OK, another question: I can see how insertion/deletion can be detected by fragment analysis, but incorporation of a wrong nucleotide wouldn't cause change in the length of amplicon, so can that also be detected by fragment analysis?
by kk
Fri Jun 06, 2014 12:16 pm
Forum: Cell Biology
Topic: How did endosymbionts coordinate replication?
Replies: 12
Views: 23559

Another question about mtDNA: what is the advantage to/role of having multiple copies of the same circular DNA molecule? Isn't that "too much of a dose" of the same given gene? Any mitochondria expert out here?