Search found 1 match

by Jessiyoo
Wed Jul 31, 2013 4:45 pm
Forum: Molecular Biology
Topic: How can depolarization activate VGCC and TRPM5
Replies: 0
Views: 1833

How can depolarization activate VGCC and TRPM5

Hi,

I know that depolarization of a cell --> activates VGCC --> Ca2+ increases --> opens TRPM5 channels to let more Ca2+ in. But my questions are:
1. What is the mechanism behind the activation of VGCC?
2. How can TRPM5 channels open (how can they sense that they have to open)?

//Jessie