- Introductory Workbook on Perl for Biology Students

Introductory Workbook on Perl for Biology Students

Dipl.Ing.S.Sai Giridhar, B.Tech., M.S.(Ph.D.)(Vienna)
Department of Computer-aided Automation
Vienna University of Technology
Vienna, Austria
Email: [email protected]


Prof.S.Krupanidhi, M.Sc., Ph.D.,
Head, Department of Biosciences,
Coordinator UGC SAP DRS, DST FIST and DBT BIF programs
Sri Sathya Sai University,
Prasanthi Nilayam 515 134 A P, India
Email:[email protected]

Department of Biosciences, Sri Sathya Sai University, Vidyagiri Complex Prasanthi Nialyam


An article submitted on January 14, 2009, published by on January 17, 2009.



The language of DNA is made up of the least number of alphabets viz., 4. A set of triplet combination of these alphabets constitute a word (codon), which is having a sense or meaning viz., defining an amino acid, the building block of proteins. There are 21 amino acids, each of them corresponds to one or more sets of triplet codons. The amino acids in various chosen combinations make up a variety of discrete proteins, reflecting on the phenotypic diversity of organisms. Consequently, the bewildering diversity around us is nevertheless being dictated by the random triplet combination of the alphabets of genomic DNA. Moreover, the array of life is being guided by the scalar variables of DNA string and the same is incidentally amenable and maneuverable for in silico tools to evaluate their virtual features.

Along with molecular tools, the in silico tools are supplementing and enriching to unravel the mysteries of genomic and proteomic analyses. The language of Perl programme conceived by Larry Wall (1987) reasonably suits as one of the best scripting languages to display a variety of diagnostic features of DNA depicted through simple exercises shown in the following pages.

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