Developing a safer form of acetaminophen
July 15, 2009 -- Scientists in Louisiana are reporting development of a process for
producing large batches of a new and potentially safer form of
acetaminophen, the widely used pain-reliever now the source of growing
concern over its potentially toxic effects on the liver. Their study,
which could speed development of a next-generation pain-reliever, is
scheduled for the July 17 issue of ACS’ Organic Process Research & Development, a bi-monthly journal.
The researchers describe a simple, efficient method for producing the new pain-reliever using only a few starting materials and a short series of chemical reactions. In laboratory studies, they used the new method to produce multigram quantities of the substance with 99 percent purity. The scientists point out that the new process can be performed on a much larger production level if needed.
--News release courtesy of American Chemical Society
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