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The study represents an initial effort to identify a set of expressed, …

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Web site references
- Data-Mining Approaches Reveal Hidden Families of Proteases in the Genome of Malaria Parasite; a catalogue and structure-based classification of proteases.; classification of peptidase (protease) families in SWISS-PROT.; official database of the malaria parasite genome project.; software for printing and shading of multiple alignment files.; software package for molecular evolutionary genetics analysis.; microarray resources provided by Dr. Joseph DeRisi at University of California, San Francisco.; Malaria Research and Reference Reagent Resource Center.

We thank Lois Blaine, David Emerson, and Thomas Nerad for their critical comments during the manuscript preparation, Truc Nguyen for computational support. This study is supported by an ATCC start-up fund to Y.W., and an NIH-grant (1R21AI49300) to Y.W. We thank the scientists and funding agencies comprising the International Malaria Genome Project for making sequence data from the genome of P. falciparum (3D7) public prior to publication of the completed sequence. The Sanger Centre (UK) provided sequence data for chromosomes 1, 3–9, and 13, with financial support from the Wellcome Trust. A consortium composed of The Institute for Genome Research, along with the Naval Medical Research Center (USA), sequenced chromosomes 2, 10, 11 & 14, with support from NIAID/NIH, the Burroughs Wellcome Fund, and the Department of Defense. The Stanford Genome Technology Center (USA) sequenced chromosome 12, with support from the Burroughs Wellcome Fund. The Plasmodium Genome Database is a collaborative effort of investigators at the University of Pennsylvania (USA) and Monash University (Melbourne, Australia), supported by the Burroughs Wellcome Fund.

The publication costs of this article were defrayed in part by payment of page charges. This article must therefore be hereby marked "advertisement" in accordance with 18 USC section 1734 solely to indicate this fact.

4 Present address: Malaria Vaccine Development Unit, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. 

5 Corresponding author. 

E-MAIL [email protected] ; FAX (703) 365-2740.

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