such as "Introduction", "Conclusion"..etc
October 23, 2008 — Many people have noticed
that as soon as you start using a skin cream, you have to continue with
it; if you stop lubricating, your skin becomes drier than when you
started. And now there is research to confirm for the first time that
normal skin can become drier from creams.
Izabela Buraczewska presents these findings in the dissertation she
is publicly defending at Uppsala University in Sweden on October 24.
The findings in Izabela Buraczewska’s dissertation confirm what many
have suspected: creams can make the skin drier. She has studied what
happens in the skin at the molecular level and also what positive and
negative effects creams have on the skin. Her research shows that
differences in the pH of creams do not seem to play any role.
Different oils were also studied in a seven-week treatment period,
but no difference was established between mineral oil and a vegetable
oil. Both oils resulted in the skin being less able to cope with
external stresses. Treatment with a more complex cream compound,
however, resulted in more resistant skin with no signs of dryness.
Tissues samples taken from the treated skin areas also show that the
weakening of the skin’s protective barrier can be tied to changes in
the activity of certain genes involved in producing skin fats, among
other functions. The conclusion is that the contents of creams impact
these effects on the skin. This knowledge enhances our potential to
develop creams that reinforce the skin’s protective barrier in a
positive way, without making the skin drier. Such creams would mean
that various groups of patients with dry skin, for example eczema and
ichthyosis, could enjoy a better quality of life.
“My findings show that creams differ and that knowledge of the
effect of various ingredients is important for us to be able to tailor
the treatment to various skin types,” says Izabela Buraczewska.
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