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<h3>Authors' contributions</h3> <p> SK and PR carried out the experiments. NK participated in work coordination and provided critical inputs during manuscript preparation. SS conceived of the study, and helped in its design and execution, and drafted the manuscript. All authors read and approved the final manuscript. </p> <a></a> <h3>Acknowledgements</h3> <p> This work was supported by internal core funds and a grant from the Department of Biotechnology, Government of India (SS and NK). SK was supported by a senior research fellowship from the Council of Scientific & Industrial Research, Government of India. The authors gratefully acknowledge Dr. Andrew Falconar for the DEN viruses and Dr. Bert Vogelstein for the pAdEasy system. The authors thank Dr. D. Chandramouli and his staff for help with the animal experiments. </p>
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