such as "Introduction", "Conclusion"..etc
January 7, 2008 -- Researchers in Italy
are reporting discovery of abnormal proteins in the saliva of autism patients
that could eventually provide a clue for the molecular basis of this severe
developmental disorder and could be used as a biomarker for a subgroup of
patients with autism spectrum disorders (ASD). Their study is in the January 2
issue of ACS’ Journal of Proteome
Research, a monthly publication.
Autism involves social withdrawal,
impaired emotional responses and communication skills, and other symptoms. With
no laboratory test available, scientists are searching for biomarkers such as
abnormal proteins that appear in the body fluids of individuals with autism that
may provide a way to accurately diagnose autism and track its response to
Massimo Castagnola, Irene Messana,
Maria Giulia Torrioli and Fiorella Gurrieri compared proteins in the saliva of
27 children with ASD to those in a control group without ASD. They discovered
that at least one of four proteins in 19 children in the ASD group had
significantly lower levels of phosphorylation. That key body process activates
proteins so that they can work normally. The results suggest that these abnormal
proteins might be the clue for anomalies in the phosphorylation of proteins
involved in development of the central nervous system in early infancy that are
involved in ASD.
This news release was provided by The American Chemical Society — a nonprofit organization chartered by the U.S. Congress
and a global leader in providing access to chemistry-related research through
its multiple databases, peer-reviewed journals and scientific conferences.
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