such as "Introduction", "Conclusion"..etc
Researchers in Massachusetts are reporting an advance in bridging huge
gaps in medical knowledge about the biochemical changes that occur
inside the eyes of individuals with diabetic retinopathy (DR) -- a
leading cause of vision loss and blindness in adults. They report
discovery of 37 proteins that were increased or decreased in the eyes
of patients with DR compared to patients without the disease.
Edward P. Feener and colleagues point out that DR is a complication
of diabetes that affects the eyesight of millions of people. It
involves damage to blood vessels in the retina, the light sensitive
tissue in the back of the eye. Physicians know that vessels grow
abnormally, swell, and leak in DR. However, they have little
understanding of the biochemical changes underlying those damaging
The researchers studied eye fluid from individuals with and without
DR who were undergoing eye surgery. They analyzed proteins in the
vitreous, the gel-like material inside the eye between the retina and
the lens. The study found 252 proteins in the fluid, including 37
proteins that showed changes that were associated with proliferative
diabetic retinopathy, the most severe form of the disease. The study
could lead to new insights into disease mechanisms and new treatments,
the article states.
Journal reference: Characterization of the Vitreous Proteome in Diabetes without
Diabetic Retinopathy and Diabetes with Proliferative Diabetic
Retinopathy" Journal of Proteome Research. June 6, 2008.
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