|
Subset of E. histolytica genes upregulated by exposure to Trichostatin A.
|
Probe ID
|
GenBank ID
|
Description
|
Fold-change
|
FDR
|
|
|
489.m00024_at
|
XM_643195
|
hypothetical protein
|
39.96
|
7.60E-16
|
14.m00310_at
|
XM_651236
|
hypothetical protein
|
39.67
|
2.32E-20
|
295.m00030_at
|
XM_644416
|
conserved hypothetical protein
|
38.77
|
2.29E-20
|
522.m00017_at
|
XM_643097
|
hypothetical protein
|
20.45
|
4.53E-15
|
418.m00028_at
|
XM_643537
|
70 kDa heat shock protein, putative
|
17.45
|
6.71E-10
|
36.m00204_s_at
|
XM_650008
|
hypothetical protein
|
14.84
|
1.22E-08
|
451.m00037_s_at
|
XM_643383
|
hypothetical protein
|
14.68
|
3.96E-04
|
556.m00022_x_at
|
XM_643031
|
hypothetical protein
|
14.37
|
5.75E-07
|
12.m00306_at
|
XM_651386
|
hypothetical protein
|
13.25
|
1.64E-05
|
376.m00054_s_at
|
XM_643784
|
hypothetical protein
|
13.02
|
1.62E-10
|
564.m00020_x_at
|
XM_643013
|
hypothetical protein
|
12.93
|
8.19E-10
|
82.m00164_s_at
|
XM_648353
|
hypothetical protein
|
12.88
|
8.00E-12
|
28.m00298_s_at
|
XM_650406
|
hypothetical protein
|
11.79
|
5.97E-09
|
110.m00118_at
|
XM_647568
|
Rho family GTPase
|
11.60
|
2.26E-14
|
50.m00195_s_at
|
XM_649449
|
hypothetical protein
|
11.36
|
3.02E-05
|
135.m00094_at
|
XM_646923
|
hypothetical protein
|
10.98
|
2.38E-08
|
493.m00030_x_at
|
XM_643175
|
hypothetical protein
|
10.25
|
1.40E-24
|
337.m00049_at
|
XM_644075
|
hypothetical protein
|
9.93
|
5.43E-07
|
164.m00105_x_at
|
XM_646368
|
hypothetical protein
|
9.92
|
4.32E-05
|
847.m00011_x_at
|
XM_642805
|
hypothetical protein
|
9.63
|
9.76E-05
|
205.m00100_s_at
|
XM_645582
|
hypothetical protein
|
9.48
|
3.01E-08
|
373.m00052_at
|
XM_643804
|
hypothetical protein
|
8.71
|
1.14E-06
|
395.m00030_x_at
|
XM_643673
|
protein kinase, putative
|
8.68
|
6.64E-04
|
749.m00013_s_at
|
XM_642848
|
hypothetical protein
|
8.61
|
1.85E-03
|
227.m00077_at
|
XM_645230
|
hypothetical protein
|
8.40
|
1.70E-08
|
728.m00012_x_at
|
XM_642855
|
hypothetical protein
|
8.37
|
5.83E-06
|
460.m00025_x_at
|
XM_643328
|
hypothetical protein
|
8.00
|
3.05E-02
|
167.m00116_x_at
|
XM_646306
|
hypothetical protein
|
7.98
|
3.77E-03
|
621.m00019_at
|
XM_642928
|
hypothetical protein
|
7.84
|
8.57E-06
|
584.m00019_at
|
XM_642979
|
heat shock protein 70, putative
|
7.82
|
5.54E-06
|
477.m00021_at
|
XM_643239
|
hypothetical protein
|
7.60
|
1.27E-03
|
123.m00123_x_at
|
XM_647209
|
conserved hypothetical protein
|
7.48
|
3.84E-05
|
76.m00146_at
|
XM_648554
|
hypothetical protein
|
7.34
|
1.75E-04
|
89.m00125_s_at
|
XM_648139
|
hypothetical protein
|
7.32
|
2.51E-05
|
220.m00068_x_at
|
XM_645332
|
hypothetical protein
|
7.14
|
2.48E-03
|
263.m00053_at
|
XM_644795
|
hypothetical protein
|
6.95
|
2.56E-04
|
804.m00006_x_at
|
XM_642821
|
hypothetical protein
|
6.94
|
2.44E-04
|
72.m00179_at
|
XM_648717
|
hypothetical protein
|
6.85
|
1.17E-04
|
211.m00072_at
|
XM_645468
|
zinc finger protein, putative
|
6.80
|
5.04E-03
|
102.m00082_at
|
XM_647784
|
hypothetical protein
|
6.74
|
6.19E-03
|
411.m00025_x_at
|
XM_643570
|
hypothetical protein
|
6.68
|
8.26E-03
|
162.m00085_at
|
XM_646412
|
predicted protein
|
6.61
|
3.81E-06
|
157.m00087_x_at
|
XM_646502
|
conserved hypothetical protein
|
6.50
|
8.44E-04
|
12.m00326_at
|
XM_651342
|
hypothetical protein
|
6.42
|
4.10E-04
|
52.m00169_x_at
|
XM_649399
|
hypothetical protein
|
6.39
|
2.21E-03
|
22.m00288_at
|
XM_650731
|
hypothetical protein
|
6.28
|
6.49E-04
|
71.m00129_at
|
XM_648728
|
hypothetical protein
|
6.16
|
5.70E-05
|
6.m00428_at
|
XM_651814
|
hypothetical protein
|
6.10
|
1.46E-04
|
496.m00027_x_at
|
XM_643167
|
hypothetical protein
|
5.98
|
9.24E-06
|
135.m00113_at
|
XM_646942
|
hypothetical protein
|
5.91
|
4.26E-03
|
|
|
|
The mean trophozoite expression value for E. histolytica 200:NIH strain under standard culture conditions, the fold-change in TSA treated parasites, FDR, GenBank ID number, and gene annotations are shown. Genes in bold have been confirmed by RT-PCR. Genes regulated during trophozoite to cyst development are shown in italics. Additional loci represented by crosshybridizing _s_at probe sets are as follows: 36.m00204_s_at: 88.m00180; 451.m00037_s_at: 467.m00031 and 50.m00196; 376.m00054_s_at: 116.m00123; 82.m00164_s_at: 82.m00157; 28.m00298_s_at: 481.m00033 and 90.m00158; 205.m00100_s_at: 105.m00129; 749.m00013_s_at: 142.m00151; 89.m00125_s_at: 357.m00038.
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Ehrenkaufer et al. BMC Genomics 2007 8:216 doi:10.1186/1471-2164-8-216
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