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<strong>Table 1.</strong> Telomere shortening during progression of CML <p> This table summarizes the data presented in seven studies of telomere length published to date. All demonstrated significantly shorter telomeres in CP CML as compared with the normal control cohort. In addition, four of five (studies 1, 3, 5, and 7) showed further (and statistically significant) shortening with disease progression. </p> <p> <sup>a</sup>Significantly shorter than CP. </p> <p> Abbreviations: AP, accelerated phase; BP, blastic phase; CML, chronic myeloid leukemia; CP, chronic phase; FISH, fluorescence in situ hybridization; kb, kilobases; MESF, molecular equivalents of soluble fluorochrome; ND, not done. </p>
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