Early Infection And Protection Against Allergies?
When infected, the body has two types of immune defence to deploy – innate immunity and acquired immunity.

Whooping Cough Immunity Lasts Longer Than Previously Thought
Immunity to whooping cough lasts at least 30 years on average, much longer than previously thought

Caveolin-1 Is Critical Regulator of Innate Immunity
A group led by Dr. You-Yang Zhou at the University of Illinois College of Medicine, Chicago, IL have discovered that caveolin-1 modulation of endothelial nitric oxide synthase (eNOS) activity regulates innate immunity and inflammation-induced lung injury.

Understanding Plants' Overactive Immune System Will Help Researchers Build Better Crops
A plant's immune system protects the plant from harmful pathogens. If the system overreacts to pathogens, it can stunt plant growth and reduce seed production.

Mounting A Multi-Layered Attack On Fungal Infections
Unravelling a microbe's multilayer defence mechanisms could lead to effective new treatments for potentially lethal fungal infections in cancer patients and others whose natural immunity is weakened.

Vaccine To Prevent Urinary Tract Infections Shows Early Promise
University of Michigan (U-M) scientists have made an important step toward what could become the first vaccine in the U.S. to prevent urinary tract infections, if the robust immunity achieved in mice can be reproduced in humans.

Key Molecular Step to Fighting Off Viruses Identified
UT Southwestern Medical Center researchers have determined how a protein that normally latches onto molecules inside cells and marks them for destruction also gives life to the body's immune response against viruses.

Women Have A More Powerful Immune System Than Men, Study Shows
When it comes to immunity, men may not have been dealt an equal hand.

Secrets of Immunologic Memory: New Understanding of CD44 Receptor's Role in Immune Cell Survival
Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham) have discovered a new way the cell surface protein, CD44, helps specific T helper (Th1) cells develop immunologic memory.

Antimicrobials Target Pathogens On Fruits And Vegetables
A novel food safety treatment tested by Agricultural Research Service (ARS) scientists could become an asset to the fast-growing fresh-cut produce industry.

An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
This work lays the foundation for developing a single Ad vector encoding EDIIIs of all four DEN serotypes to evoke a balanced immune response against each one of them.

Efficiency of the immunome protein interaction network increases during evolution
A recent definition of a reference set of proteins essential for the human immunome, combined with information about protein interaction networks for these proteins, facilitates evolutionary study of this biological machinery.

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
These data suggest that differences in immunodominance patterns might explain the incomplete response overlap, and that with limitations; HLA Tg mice represent a relevant and suitable model system to study immune responses against complex pathogens.

Why Don't Mothers' Bodies Reject Their Fetus?
The immune system is designed to attack anything that is not the body's own tissues, such as pathogens and genetically nonidentical organ transplants, so why does the maternal immune system not attack a developing fetus?

Trapping Immune Cells In The Uterus Prevents Anti-fetal Immunity
Why the immune system of a pregnant woman does not attack her developing fetus is one of most remarkable features of pregnancy, and several underlying mechanisms have been described.

Connection Between Allergic Diseases And Autoimmune Diseases
Researchers at Children’s and the University of Washington identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases.

Autoantibodies Help T Cells 'See' Their Target
Autoimmune diseases such as type I diabetes and rheumatoid arthritis are caused by the immune system attacking the body's own tissues.

Treating Type 1 Diabetes By Eliminating B Cells
Autoimmune diseases such as type 1 diabetes and rheumatoid arthritis (RA) are caused when immune cells known as lymphocytes attack our own body tissues.

B Cells Can Act Alone In Autoimmune Disease
B cells, the source of damaging autoantibodies, have long been thought to depend upon T cells for their activation and were not considered important in the initiation of autoimmune diseases....

How Superbugs Control Their Lethal Weapons
It appears that some superbugs have evolved to develop the ability to manipulate the immune system to everyone's advantage.