An adenovirus prime/plasmid boost strategy for induction of equipotent immune responses to two dengue virus serotypes
This work lays the foundation for developing a single Ad vector encoding EDIIIs of all four DEN serotypes to evoke a balanced immune response against each one of them.

Efficiency of the immunome protein interaction network increases during evolution
A recent definition of a reference set of proteins essential for the human immunome, combined with information about protein interaction networks for these proteins, facilitates evolutionary study of this biological machinery.

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?
These data suggest that differences in immunodominance patterns might explain the incomplete response overlap, and that with limitations; HLA Tg mice represent a relevant and suitable model system to study immune responses against complex pathogens.

Why Don't Mothers' Bodies Reject Their Fetus?
The immune system is designed to attack anything that is not the body's own tissues, such as pathogens and genetically nonidentical organ transplants, so why does the maternal immune system not attack a developing fetus?

Trapping Immune Cells In The Uterus Prevents Anti-fetal Immunity
Why the immune system of a pregnant woman does not attack her developing fetus is one of most remarkable features of pregnancy, and several underlying mechanisms have been described.

Connection Between Allergic Diseases And Autoimmune Diseases
Researchers at Children’s and the University of Washington identifies a connection between allergic diseases such as atopic dermatitis, also known as eczema, and autoimmune diseases.

Autoantibodies Help T Cells 'See' Their Target
Autoimmune diseases such as type I diabetes and rheumatoid arthritis are caused by the immune system attacking the body's own tissues.

Treating Type 1 Diabetes By Eliminating B Cells
Autoimmune diseases such as type 1 diabetes and rheumatoid arthritis (RA) are caused when immune cells known as lymphocytes attack our own body tissues.

B Cells Can Act Alone In Autoimmune Disease
B cells, the source of damaging autoantibodies, have long been thought to depend upon T cells for their activation and were not considered important in the initiation of autoimmune diseases....

How Superbugs Control Their Lethal Weapons
It appears that some superbugs have evolved to develop the ability to manipulate the immune system to everyone's advantage.

Crossroads ofextrathymic lymphocytesmaturation pathways
Hypothesis that microbes, especially viruses, can be promoters of extrathymic (self)antigen-reactive lymphocytes maturation is real ....

Early immune system exposures linked to chronic disease
Scientists and regulators have a golden opportunity to reduce the health toll from a range of diseases by focusing more attention on identification of environmental factors that can damage the prenatal immune system

MSU researchers make new discoveries on what does and doesn't affect immune system
Scientists know that a number of factors can affect the body's immune system

Researchers discover new battleground for viruses and immune cells
Finding should aid those developing anti-virus vaccines

Tattooing improves response to DNA vaccine
A tattoo can be more than just a fashion statement - it has potential medical value

NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system

Some cases of autism may be traced to the immune system of mothers during pregnancy
UC-Davis discovery could lead to prenatal identification and prevention

Gene therapy protocol at UCSD activates immune system in patients with leukemia
Researchers inserted a gene with the potential to activate an immune response...

A functional immune system can be derived from embryonic stem cells, preliminary study finds
A new study demonstrates for the first time that embryonic stem cells can be used to create functional immune system blood cells

Bacterial toxin closes gate on immune response, Penn researchers discover
Implications for finding new ways to fight MRSA