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Bioinformatics is an information technology applied in biological research to store, collect and retrieve biologically oriented data, to analyze and predict the composition of molecules (nucleic acids, proteins, etc.), and to model biological systems through mathematical, statistical and computer methods. Major studies in this field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.

Bioinformatics Articles

Whole Genome Sequencing Towards Individualized Cancer Care
Whole Genome Sequencing or WGS is a process that looks at the whole genome. Discover how WGS can help in creating a more effective treatment regimen for cancers

Date: 5 Apr 2011, Rating: 4.54

Catching The Common Cold Virus Genome
A new study by Brigham Young University researchers on the virus behind nearly half of all cold infections explains how and where evolution occurs in the rhinovirus genome and what this means for possible vaccines.

Date: 7 Mar 2010, Rating: 5.00

After 5 Years, Free Systems Biology Markup Language Has Proven Popular
A scientific paper that describes a file format used by scientists to represent models of biological processes has exceeded 500 citations in the ISI Web of Knowledge, an online academic database that documents the impact of scientific publications.

Date: 7 Mar 2010, Rating: not rated

New Software To Understand Viruses
Computer scientists and biologists at the University of Southampton have used the combined power of computing resources within the institution to develop software which provides a better understanding of how viruses evolve.

Date: 7 Mar 2010, Rating: 5.00

Toward A Systems Biology Map Of Iron Metabolism
Scientists have taken the first steps toward constructing a systems biology map of iron metabolism.

Date: 7 Mar 2010, Rating: not rated

What It Might Take to Unravel the 'Lean Mean Machine' That Is Cancer
Scientists describe gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago.

Date: 7 Mar 2010, Rating: not rated

New 3-D Structural Model Of Critical H1N1 Protein Developed
In just two weeks from the time the first patient virus samples were made available, Singapore scientists report an evolutionary analysis of a critical protein produced by the 2009 H1N1 influenza A virus strain.

Date: 7 Mar 2010, Rating: not rated

Compendium Of Pancreatic Cancer Biomarkers Established As Strategic Approach To Early-Detection
A cancer scientist from Johns Hopkins has convinced an international group of colleagues to delay their race to find new cancer biomarkers

Date: 7 Mar 2010, Rating: not rated

New Computational Tool for Cancer Treatment
Many human tumors express indoleamine 2,3-dioxygenase (IDO), an enzyme which mediates an immune-escape in several cancer types.

Date: 7 Mar 2010, Rating: 4.00

Darwin Meets Facebook: Social Networking Tool Lets Natural Historians Share Data
Natural history plans to chart life on earth, yet the discipline risks being buried under a landslide of painstakingly collected data that isn't always used.

Date: 7 Mar 2010, Rating: not rated

Bioinformatics Sheds Light On Evolutionary Origin Of Rickettsia Virulence Genes
Scientists have revealed that genes for a specific type of molecular secretion system in Rickettsia, a structure that is linked in many cases to virulence, have been conserved over many years of evolution.

Date: 7 Mar 2010, Rating: not rated

Introductory Workbook on Perl for Biology Students
Perl script is designed to visualize virtually the features of nucleotide strings. In the present endeavour, a few exercises are conceived to unravel the inherent features of DNA using perl script.

Date: 30 Jan 2009, Rating: 3.70, 19 pages

The MPI Bioinformatics Toolkit for protein sequence analysis
The MPI Bioinformatics Toolkit is an interactive web service which offers access to a great variety of public and in-house bioinformatics tools.

Date: 28 Oct 2008, Rating: 4.00, 9 pages

Poxvirus Bioinformatics Resource Center: a comprehensive Poxviridae informational and analytical resource
The Poxvirus Bioinformatics Resource Center has been established to provide informational and analytical resources to the scientific community to aid research directed at providing a better understanding of the Poxviridae family of viruses.

Date: 28 Oct 2008, Rating: 4.50, 13 pages

Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells
Although a huge amount of mammalian genomic data does become publicly available, there are still hurdles for biologists to overcome before such data can be fully exploited.

Date: 28 Oct 2008, Rating: 2.00, 13 pages

Genomics of large marine animals showcased in the Biological Bulletin
Though the slow moving purple sea urchin may look oblivious, lacking a head, eyes and ears, this prickly creature has an impressive suite of sensory receptors to detect outside signals.

Date: 27 Oct 2008, Rating: not rated

Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
As Aesop said, appearances are deceiving—even in life's tiniest critters.

Date: 27 Oct 2008, Rating: not rated

After the first decade of metagenomics -- adolescent growth spurt anticipated
Mostly hidden from the scrutiny of the naked eye, microbes have been said to run the world.

Date: 27 Oct 2008, Rating: not rated

Complete Genomics launches, becomes world's first large-scale human genome sequencing company
Complete Genomics Inc., a third-generation human genome sequencing company, today announced its formal launch as the world's first provider of large-scale human genome sequencing services.

Date: 27 Oct 2008, Rating: 4.00

Diatom genome helps explain success in trapping excess carbon in oceans
Diatoms, mighty microscopic algae, have profound influence on climate, producing 20 percent of the oxygen we breathe by capturing atmospheric carbon and in so doing, countering the greenhouse effect.

Date: 27 Oct 2008, Rating: 5.00