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Biology Articles » Bioinformatics

Bioinformatics

Bioinformatics is an information technology applied in biological research to store, collect and retrieve biologically oriented data, to analyze and predict the composition of molecules (nucleic acids, proteins, etc.), and to model biological systems through mathematical, statistical and computer methods. Major studies in this field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.


Bioinformatics Articles

Introductory Workbook on Perl for Biology Students
Perl script is designed to visualize virtually the features of nucleotide strings. In the present endeavour, a few exercises are conceived to unravel the inherent features of DNA using perl script.

Date: 30 Jan 2009, Rating: 3.74, 19 pages

The MPI Bioinformatics Toolkit for protein sequence analysis
The MPI Bioinformatics Toolkit is an interactive web service which offers access to a great variety of public and in-house bioinformatics tools.

Date: 28 Oct 2008, Rating: 3.00, 9 pages

Poxvirus Bioinformatics Resource Center: a comprehensive Poxviridae informational and analytical resource
The Poxvirus Bioinformatics Resource Center has been established to provide informational and analytical resources to the scientific community to aid research directed at providing a better understanding of the Poxviridae family of viruses.

Date: 28 Oct 2008, Rating: not rated, 13 pages

Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells
Although a huge amount of mammalian genomic data does become publicly available, there are still hurdles for biologists to overcome before such data can be fully exploited.

Date: 28 Oct 2008, Rating: 2.00, 13 pages

Genomics of large marine animals showcased in the Biological Bulletin
Though the slow moving purple sea urchin may look oblivious, lacking a head, eyes and ears, this prickly creature has an impressive suite of sensory receptors to detect outside signals.

Date: 27 Oct 2008, Rating: not rated

Genome of simplest animal reveals ancient lineage, confounding array of complex capabilities
As Aesop said, appearances are deceiving—even in life's tiniest critters.

Date: 27 Oct 2008, Rating: not rated

After the first decade of metagenomics -- adolescent growth spurt anticipated
Mostly hidden from the scrutiny of the naked eye, microbes have been said to run the world.

Date: 27 Oct 2008, Rating: not rated

Complete Genomics launches, becomes world's first large-scale human genome sequencing company
Complete Genomics Inc., a third-generation human genome sequencing company, today announced its formal launch as the world's first provider of large-scale human genome sequencing services.

Date: 27 Oct 2008, Rating: not rated

Diatom genome helps explain success in trapping excess carbon in oceans
Diatoms, mighty microscopic algae, have profound influence on climate, producing 20 percent of the oxygen we breathe by capturing atmospheric carbon and in so doing, countering the greenhouse effect.

Date: 27 Oct 2008, Rating: not rated

Human protein atlas will help pinpoint disease
Researchers in Sweden are compiling a remarkable 'atlas' that pinpoints the location of thousands of individual proteins in the body's tissues and cells...

Date: 27 Oct 2008, Rating: 2.67

Development puts an end to the evolution of endless forms
Researchers have put forward a simple model of development and gene regulation that is capable of explaining patterns observed in the distribution of morphologies and body plans (or, more generally, phenotypes).

Date: 27 Oct 2008, Rating: not rated

Prediction of binding sites of interleukin1 type1 receptors involved in osteoarthritis
Article on prediction of binding sites of interleukin receptor type1 using bioinformatics approach.

Date: 4 Oct 2008, Rating: 5.00, 5 pages

Conformational analysis of alternative protein structures
Alternative structural models determined experimentally are available for an increasing number of proteins.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

MDQC: a new quality assessment method for microarrays based on quality control reports
The process of producing microarray data involves multiple steps, some of which may suffer from technical problems and seriously damage the quality of the data.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

The Molecular Biology Database Collection: 2008 update
The Nucleic Acids Research online Molecular Biology Database Collection is a public repository that lists more than 1000 databases described in this and previous Nucleic Acids Research annual database issues

Date: 1 Dec 2007, Rating: not rated, 3 pages

Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria
ERIC, the Enteropathogen Resource Integration Center is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense

Date: 1 Dec 2007, Rating: 3.00, 14 pages

Functional profiling of microarray experiments using text-mining derived bioentities
The increasing use of microarray technologies brought about a parallel demand in methods for the functional interpretation of the results.

Date: 1 Dec 2007, Rating: not rated, 9 pages

A semantic web approach applied to integrative bioinformatics experimentation: a biological use case with genomics data
The numerous public data resources make integrative bioinformatics experimentation increasingly important in life sciences research.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

Computer program traces ancestry using anonymous DNA samples
A group of computer scientists, mathematicians, and biologists from around the world have developed a computer algorithm that can help trace the genetic ancestry of thousands of individuals in minutes

Date: 1 Dec 2007, Rating: 3.00

Smithsonian scientists help lead effort to 'barcode' world's species
Smithsonian researchers are among the leaders in a worldwide effort to revolutionize the way scientists identify species in the laboratory and in the field with a technique called DNA barcoding.

Date: 1 Dec 2007, Rating: 3.00