Tearing down the fungal cell wall
Scientists have pinpointed a fungal gene that appears to play an important role in the development and virulence of Alternaria brassicicola.

Proteins may predict lung transplant rejection
Using the latest in high tech tools, researchers have identified three proteins that were highly predictive of chronic lung rejection up to 20 months before the rejection occurred.

Mining yeast in silico unearths a golden nugget for mitochondrial biology
The research described here combines clever model organism genomics and bioinformatics with sophisticated human molecular and biochemical genetics to identify the first mammalian protein required for the normal assembly of complex I.

Computers to save unique type of American red squirrel
UK expertise is being exported to North America to help prevent a unique type of red squirrel dying out in as little as 30 years time.

Experimental and bioinformatic approaches for interrogating protein–protein interactions to determine protein function
The authors presented an overview of different experimental and bioinformatic methods to elucidate protein–protein interactions.

Computational cluster validation in post-genomic data analysis
This review paper aims to familiarize the reader with the battery of techniques available for the validation of clustering results, with a particular focus on their application to post-genomic data analysis.

From genome to epigenome
The authors reviewed the current thinking and progress on how to get from the genome to the epigenome(s) and discuss some potential applications.

Bioinformatics as a critical prerequisite to transcriptome and proteome studies
This paper will provide some examples of misleading annotations with regard to putative protein function that may cause mistakes either in array design or in data interpretation.

Bioinformatics opportunities for health sciences librarians and information professionals
The aim of this brief communication is to assist health sciences librarians with finding training programs and to give examples of how some libraries are currently expanding services to support bioinformatics research.

Introduction. Bioinformatics: from molecules to systems
One contribution of 15 to a Discussion Meeting Issue 'Bioinformatics: from molecules to systems'.

Researchers simulate complete structure of virus -- on a computer
News: the first computer simulation of an entire life form -- a virus-- has been completed...

HortResearch science reveals the natural potential of apples
Fruit lovers worldwide may soon enjoy new, healthier, tastier apples, following the release this week of crucial genetic data which fruit breeders say will help revolutionise the produce industry.

Computer scientist sorts out confusable drug names
Was that Xanex or Xanax? Or maybe Zantac? If you're a health care professional you'd better know the difference--mistakes can be fatal.

Powerful new tool for studying brain development
Scientists have given investigators around the world free access to a powerful tool for studying brain development.

NYU algorithm enhances ability to detect cancer genes
Researchers have developed a new algorithm that enhances the ability to detect a cancer gene, and have applied their algorithm to map the set of tumor-suppressor genes involved in lung cancer.

Computational model simulates AZT metabolism in mitochondria
Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a computational model that allows scientists to better understand the metabolism and toxicity of the HIV/AIDS drug zidovudine (azidothymidine, AZT).

Researchers Teach Computers How to Name Images By 'Thinking'
Penn State researchers have "taught" computers how to interpret images using a vocabulary of up to 330 English words...

Bioinformatics in microbial biotechnology – a mini review
For the last decade, bioinformatics techniques have been developed to identify and analyze various components of cells such as gene and protein function, interactions, and metabolic and regulatory pathways. The next decade will belong to understanding cel

In silico identification and comparative analysis of differentially expressed genes in human and mouse tissues
Large-scale expressed sequence tag (EST) – based bioinformatics analysis deal with the heterogenous tissue and organ terms used to describe EST libraries due to the rich libraries and tremendous amount of data available in the public domain.

New Recipe for Discovery: An Online Blend of Worms, Flies, Yeast
A new computational approach that integrates data about how genes interact with each other in roundworms, fruit flies and yeast was recently developed. This serves as a valuable resource for biologists, who might first do a quick online query to learn new