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Biology Articles » Bioinformatics


Bioinformatics is an information technology applied in biological research to store, collect and retrieve biologically oriented data, to analyze and predict the composition of molecules (nucleic acids, proteins, etc.), and to model biological systems through mathematical, statistical and computer methods. Major studies in this field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.

Bioinformatics Articles

Human protein atlas will help pinpoint disease
Researchers in Sweden are compiling a remarkable 'atlas' that pinpoints the location of thousands of individual proteins in the body's tissues and cells...

Date: 27 Oct 2008, Rating: 2.25

Development puts an end to the evolution of endless forms
Researchers have put forward a simple model of development and gene regulation that is capable of explaining patterns observed in the distribution of morphologies and body plans (or, more generally, phenotypes).

Date: 27 Oct 2008, Rating: not rated

Prediction of binding sites of interleukin1 type1 receptors involved in osteoarthritis
Article on prediction of binding sites of interleukin receptor type1 using bioinformatics approach.

Date: 4 Oct 2008, Rating: 4.75, 5 pages

Conformational analysis of alternative protein structures
Alternative structural models determined experimentally are available for an increasing number of proteins.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

MDQC: a new quality assessment method for microarrays based on quality control reports
The process of producing microarray data involves multiple steps, some of which may suffer from technical problems and seriously damage the quality of the data.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

The Molecular Biology Database Collection: 2008 update
The Nucleic Acids Research online Molecular Biology Database Collection is a public repository that lists more than 1000 databases described in this and previous Nucleic Acids Research annual database issues

Date: 1 Dec 2007, Rating: not rated, 3 pages

Enteropathogen Resource Integration Center (ERIC): bioinformatics support for research on biodefense-relevant enterobacteria
ERIC, the Enteropathogen Resource Integration Center is a new web portal serving as a rich source of information about enterobacteria on the NIAID established list of Select Agents related to biodefense

Date: 1 Dec 2007, Rating: 4.00, 14 pages

Functional profiling of microarray experiments using text-mining derived bioentities
The increasing use of microarray technologies brought about a parallel demand in methods for the functional interpretation of the results.

Date: 1 Dec 2007, Rating: 5.00, 9 pages

A semantic web approach applied to integrative bioinformatics experimentation: a biological use case with genomics data
The numerous public data resources make integrative bioinformatics experimentation increasingly important in life sciences research.

Date: 1 Dec 2007, Rating: 1.00, 8 pages

Computer program traces ancestry using anonymous DNA samples
A group of computer scientists, mathematicians, and biologists from around the world have developed a computer algorithm that can help trace the genetic ancestry of thousands of individuals in minutes

Date: 1 Dec 2007, Rating: 3.00

Smithsonian scientists help lead effort to 'barcode' world's species
Smithsonian researchers are among the leaders in a worldwide effort to revolutionize the way scientists identify species in the laboratory and in the field with a technique called DNA barcoding.

Date: 1 Dec 2007, Rating: 4.00

Primate behavior explained by computer 'agents'
The complex behaviour of primates can be understood using artificially-intelligent computer ‘agents’ that mimic their actions, shows new research

Date: 1 Dec 2007, Rating: not rated

1 sample examined by 1,000 pathologists -- how and why?
More than eight hundred pathologists from around Europe and the world will take part in a first of its kind, large-scale virtual microscopy slide seminar on the web.

Date: 1 Dec 2007, Rating: not rated

Computers help chemists fight emerging infections
Computer analysis of existing drugs may be key to fighting new infectious agents and antibiotic-resistant pathogens like deadly tuberculosis strains and staph ‘superbugs.’

Date: 1 Dec 2007, Rating: not rated

New algorithm matches any tumor cells to best possible anti-cancer treatments
Cancer patients don’t have time to waste. Many go through several different treatments, however, to find one that is more effective against their particular type of tumor.

Date: 1 Dec 2007, Rating: not rated

Charting ever-changing genomes
Instead of immutable proprietary software, any species’ genetic information resembles open source code that is constantly tweaked and optimized to meet the users’ specific needs.

Date: 1 Dec 2007, Rating: 1.00

Computers learn how to create drugs of the future
The key role of computer technology in the fine-tuning of drug development and design will be considered by Professor Stephen Muggleton of Imperial College

Date: 1 Dec 2007, Rating: 3.00

Chemistry of a cuppa: Helping to digitize the laboratories of tomorrow
The brewing of tea formed a crucial component of a project which successfully took traditional paper laboratory books and moved them to digital formats.

Date: 1 Dec 2007, Rating: not rated

Scientists identify 36 genes, 100 neuropeptides in honey bee brains
Using a combination of the newly available honey bee genome sequence, as well as bioinformatics and mass spectrometry, scientists inferred the sequences of more than 200 possible neuropeptides from the brain of the honey bee.

Date: 1 Dec 2007, Rating: 4.00

Rickettsia felis, a cat-flea-borne pathogen, sheds light on Rickettsial evolution
VBI researchers have created a new classification system for rickettsia bacteria that may assist researchers in the way they approach the development of diagnostics and vaccines for the virulent rickettsial pathogens.

Date: 1 Dec 2007, Rating: not rated