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Home » Biology Articles » Biochemistry » Nucleic Acid Biochemistry

Nucleic Acid Biochemistry

Articles on the structure, characteristics, function and mode of action of nucleic acids

Nucleic Acid Biochemistry Articles

Peptide nucleic acid–DNA duplexes: Long range hole migration from an internally linked anthraquinone
The discovery that peptide nucleic acids (PNA) mimic DNA and RNA by forming complementary duplex structures following Watson–Crick base pairing rules opens fields in biochemistry, diagnostics, and medicine for exploration.

Date: 25 Sep 2008, Rating: 5.00, 7 pages

Series Introduction: Emerging clinical applications of nucleic acids
Attempts to employ nucleic acids in gene therapy have become commonplace in recent years, but efficient gene transfer methods have proved unexpectedly difficult to devise, and safety concerns linger.

Date: 25 Sep 2008, Rating: not rated, 5 pages

Unregulated Hazards ‘Naked’ and ‘Free’ Nucleic Acids
A huge variety of naked/free nucleic acids are being produced in the laboratory and released unregulated into the environment.

Date: 25 Sep 2008, Rating: 4.00, 15 pages

Electronic Structure Of DNA Revealed For First Time
Utilizing a technique that combines low temperature measurements and theoretical calculations, scientists have revealed for the first time the electronic structure of single DNA molecules.

Date: 25 Sep 2008, Rating: 5.00

Nanotechnology Innovation May Revolutionize Gene Detection In A Single Cell
Scientists at Arizona State University's Biodesign Institute have developed the world's first gene detection platform made up entirely from self-assembled DNA nanostructures.

Date: 25 Sep 2008, Rating: not rated

First DNA Molecule Made Almost Entirely Of Artificial Parts
Chemists in Japan report development of the world's first DNA molecule made almost entirely of artificial parts.

Date: 25 Sep 2008, Rating: 1.50

Real-time Observation Of DNA-repair Mechanism
For the first time, researchers at Delft University of Technology have witnessed the spontaneous repair of damage to DNA molecules in real time.

Date: 25 Sep 2008, Rating: 3.00

Scientists Make Chemical Cousin Of DNA For Use As New Nanotechnology Building Block
Researchers are continually on the lookout for new building blocks to push innovation and discovery to scales much smaller than the tiniest speck of dust.

Date: 25 Sep 2008, Rating: 4.50

DNA Sewing Machine Manipulates Delicate DNA Chains Without Breaking Them
Japanese scientists have made a micro-sized sewing machine to sew long threads of DNA into shape.

Date: 25 Sep 2008, Rating: not rated

How Did Chemical Constituents Essential To Life Arise On Primitive Earth?
Experiments show that simple molecules can combine chemically rather than biologically to form the building blocks of DNA

Date: 25 Sep 2008, Rating: 5.00

Post-transcriptional nucleotide modification and alternative folding of RNA
Alternative foldings are an inherent property of RNA and a ubiquitous problem in scientific investigations.

Date: 19 Nov 2007, Rating: 4.67, 5 pages

Reverse Polarization in Amino acid and Nucleotide Substitution Patterns Between Human–Mouse Orthologs of Two Compositional Extrema
Genome-wide analysis of sequence divergence patterns in 12 024 human–mouse orthologous pairs reveals

Date: 19 Nov 2007, Rating: 5.00, 8 pages

New way to label nucleic acids could lead to new therapies
Nucleic acids embrace many more kinds of molecules than just giant strands of DNA and RNA, and several forms have shown promise for therapy.

Date: 18 Nov 2007, Rating: not rated

Renegade RNA -- Clues to cancer and normal growth
Researchers at Johns Hopkins have discovered that a tiny piece of genetic code apparently goes where no bit of it has gone before, and it gets there under its own internal code.

Date: 18 Nov 2007, Rating: 3.00

Molecule crucial for processing non-coding RNA identified
Long-standing scientific question resolved

Date: 18 Nov 2007, Rating: not rated

RNA splicing occurs in nerve-cell dendrites
Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger RNA

Date: 18 Nov 2007, Rating: 5.00

CSHL shows correcting rna splicing may help treat spinal muscular atrophy
RNA splicing antisense technology studied at Cold Spring Harbor Laboratory (CSHL) effectively corrected an mRNA splicing defect found in spinal muscular atrophy (SMA) patients

Date: 18 Nov 2007, Rating: not rated

A brave new "old world" of RNA
A new function for RNA, which further elucidates how genes are expressed and regulated, is described on the 25th of November issue of the journal Nature.

Date: 18 Nov 2007, Rating: not rated

Towards a unified model of transcription termination
A new, unified model for transcription termination by RNA Poymerase II...

Date: 18 Nov 2007, Rating: 5.00

Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
The distribution of the four nucleotides along the DNA sequence encodes the genetic information in living systems.

Date: 18 Nov 2007, Rating: 4.00