The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts
The authors using biochemical process further deciphered the mechanism of action of clopidogrel and of its active metabolite (Act-Met) on P2Y12 receptors.

Serum butyrylcholinesterase in type 2 diabetes mellitus: a biochemical and bioinformatics approach
Butyrylcholinesterase is an enzyme that may serve as a marker of metabolic syndrome.

The lipid lowering effect of plant sterol ester capsules in hypercholesterolemic subjects
The present study was designed to confirm the efficacy of the plant sterol esters (PSE) in capsule form on lipid profile lowering in free-living hypercholesterolemic subjects during a short term (4 weeks).

Opposing Fat Metabolism Pathways Triggered By A Single Gene
Regulating metabolism of fat is an important challenge for any animal, from nematodes to humans.

Hormone Discovery Points To Benefits Of 'Home Grown' Fat
A hormone found at higher levels when the body produces its own "home grown" fat comes with considerable metabolic benefits

Fat Chance: Brown Vs. White Fat Cell Specification
Researchers elucidate the molecular pathway that induces cells to become energy-burning brown fat cells as opposed to energy-storing white fat cells.

Enzyme Could Provide Continual Fat Burning
An enzyme discovered by Baylor College of Medicine researchers is critical to the metabolic pathway that governs the body's ability to burn fat

Atomic Structure Of The Mammalian 'Fatty Acid Factory' Determined
Researchers at ETH Zurich have determined the atomic structure of a mammalian fatty acid synthase.

Anti-inflammatory Effects Of Omega 3 Fatty Acid In Fish Oil Linked To Lowering Of Prostaglandin
The biochemical basis for these beneficial health effects is not well understood.

Bears And Hibernation: New Insights Into Metabolism In Extreme Conditions
ue to their ability to produce a potent inhibitor of protein degradation, hibernating bears do not lose muscle mass after long periods of hibernation.

The atherogenic and metabolic impact of non-HDL cholesterol versus other lipid sub-components among non-diabetic and diabetic Saudis
This study supports the use of non-HDL cholesterol as the more practical and reliable target for lipid lowering therapy among the Saudi population.

Conformational study of the protegrin-1 (PG-1) dimer interaction with lipid bilayers and its effect
In order to understand the dimeric effects leading to membrane damage, extensive molecular dynamics simulations were performed for the β-sheets of the PG-1 dimer in explicit water, salt, and lipid bilayers composed of POPC lipids.

Effects of anethum graveolens and garlic on lipid profile in hyperlipidemic patients
Anethum has no significant effect on lipid profile, but garlic tablet has significant favorable effect on cholesterol, LDL-cholesterol, and HDL-cholesterol.

Alterations in lipid metabolism gene expression and abnormal lipid accumulation in fibroblast explants from giant axonal neuropathy patients
The goal of this study was to examine global alterations in gene expression in fibroblasts derived from newly identified GAN families compared with normal cells.

Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in patients with osteoarthritis
This work was undertaken to assess oxidative stress and antioxidant status in patients with osteoarthritis.

Molecular fats prevent nerve sheath abnormality
A study led by scientists at the University of North Carolina at Chapel Hill points to a group of lipids (fats) that are crucial to proper formation of the myelin sheath surrounding nerve fibers.

Linking the immune system with lipid metabolism
Scientists have discovered a family of proteins that connect the immune system to the body's lipids

Lipids play important role in nervous system development
Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found.

New lipid molecule holds promise for gene therapy
Scientists at the University of California, Santa Barbara have created a new molecule that holds promise in fighting disease via gene therapy.

Lipid plays big role in embryonic development
A little-known lipid plays a big role in helping us grow from a hollow sphere of stem cells into human beings, researchers have found.