Yolk sac tumour
yolk sac tumour --> endodermal sinus tumour
An unusual and aggressive tumour of germ-cell origin that reproduces the extraembryonic structures of the early embryo. It is the most common malignant germ cell tumour found in children. It is characterised by a labyrinthine glandular pattern of flat epithelial cells and rounded papillary processes with a central capillary (schiller-duval body). The tumour is rarely bilateral. Before the use of combination chemotherapy, the tumour was almost invariably fatal.