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Y-linked inheritance

Y-linked inheritance

inheritance by genes on the y chromosome. Also called holandric inheritance.


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meiome and genome

I thought eukaryote genetic inheritance came simply from the adding together of (recombinant) haploid chromosomes in the new zygote. But there is a lot of RNA involved? A crowd of unique proteins and mRNA in addition to the chromosomes ...

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by mattw
Sun May 05, 2013 2:58 am
 
Forum: Genetics
Topic: meiome and genome
Replies: 0
Views: 1743

Re: Muscular dystrophy inheritance question

Right - this is autosomal, therefore it is not Duchenne muscular dystrophy (DMD) and is not a mutation of the dystrophin gene. Thanks, I had missed that. The upper sequences look identical, while the lower sequences show two different sequences for the female (due to the N position, which shows two ...

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by jonmoulton
Thu Jan 10, 2013 3:59 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 4253

Re: Muscular dystrophy inheritance question

... and 1 wildtype (lower sequence) and is therefore unaffected as it is recessive. I am not sure if muscular dystrophy actually shows this type of inheritance or if my lecturer made that up, but based on the fact that we were told it's autosomal recessive I'm guessing the woman must have 2 mutations ...

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by firefly
Wed Jan 09, 2013 9:16 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 4253

Re: Muscular dystrophy inheritance question

The lower sequence shows one trace for the male but for the female there are two traces at one nucleotide position (labelled N). That looks like the allelic difference; since the female has two copies of the dystrophin gene that differ slightly, this can give rise to the two traces in the sequence (...

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by jonmoulton
Wed Jan 09, 2013 5:06 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 4253

Muscular dystrophy inheritance question

"The figure shows a family with muscular dystrophy showing autosomal recessive inheritance. Genomic DNA was sequenced and the two mutations are shown for the affected. The corresponding control sequence for that region of the gene X is also shown. Describe the ...

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by firefly
Mon Jan 07, 2013 8:35 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 4253
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