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Wobble

wobble

In molecular biology, unorthodox pairing between the base at the 5' end of an anticodon and the base that pairs with it (in the 3'-position of the codon); thus, the anticodon 3'-UCU-5' may pair with 5'-AGA-3' (normal or Watson-crick pairing) or with 5'-AGG-3' (wobble). Wobble pairings can occur between the unusual base hypoxanthine and adenine, uracil, or cytosine, between uracil and guanine, and between guanine and uracil, when in the 5'-position of an anticodon.

See: wobble base.


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Re: I am afraid to ask but, High school freshman - Honors Class

For the specific question you asked, look into the term "wobble base". Your daughter is going to need to do a lot of reading quickly. That's good. Use Wikipedia - while it's not a "final authority", many of the biology pages are pretty ...

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by jonmoulton
Thu Sep 11, 2008 12:24 am
 
Forum: Molecular Biology
Topic: I am afraid to ask but, High school freshman - Honors Class
Replies: 15
Views: 2847

Re: Morpholino review: how to knockdown

... divergence but can complement the missing protein's activity) or using a Morpholino that targets the start of the coding sequence and introducing wobble-base mutations at five or more positions in the start of the rescue mRNA coding sequence (however, while there have been some reports of success ...

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by jonmoulton
Thu Jul 31, 2008 9:30 pm
 
Forum: Molecular Biology
Topic: Morpholino review: how to knockdown
Replies: 7
Views: 1739

A quick Question that needs to be answered tonight

Wobble is not the redundancy of the genetic code. It is a phenomenon. But since you don't know the basics, I won't start with the more advanced stuff just yet...

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by MrMistery
Mon May 19, 2008 8:33 pm
 
Forum: Genetics
Topic: A quick Question that needs to be answered tonight
Replies: 3
Views: 976

A quick Question that needs to be answered tonight

The redundancy of the genetic code is called “wobble”. Which base of the triplet pair seems to be the least influential in determining the amino acid coded for? (1st, 2nd. or 3rd) Why would this wobble be beneficial to an organism in an evolutionary ...

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by clay5486
Mon May 19, 2008 12:22 am
 
Forum: Genetics
Topic: A quick Question that needs to be answered tonight
Replies: 3
Views: 976

Isoleucine anti-codons

In can in theory. But I can pair with either C, U or A(wobble). So you see, UAI can pair with no problems with all three codons. I have never heard of the absence of the UAU anticodon, but then again, i don't know them all by heart. But because UAI ...

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by MrMistery
Wed Mar 12, 2008 12:14 pm
 
Forum: Cell Biology
Topic: Isoleucine anti-codons
Replies: 3
Views: 1059
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