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Wilms tumour

wilms tumour

(Science: radiology) Nephroblastoma, 3rd most common kiddie tumour (most common abdominal tumour), arises from embryonal renal tissue (nephroblastomatosis), large, only 10% are calcified, 4-10% bilateral, metastasis may lead to lungs, para-aortic nodes associated with: aniridia, beckwith-Wiedemann syndrome, hemihypertrophy, drash syndrome cf: neuroblastoma (more likely calcified) Wilm's tumour

(Science: oncology, tumour) wilm's tumour or nephroblastoma, is a cancerous tumour of the kidney in children.

Wilm's is the most common tumour of the kidney and the most common intra-abdominal tumour in children. The exact cause is unknown, but probably develops in foetal tissue due to an underlying genetic factor. Like retinoblastoma, both sporadic and inherited forms occur.

Believed to be caused by development of homozygosity for a deletion of the tip of the short arm of chromosome 11, which is presumed to contain a tumour suppressor gene. Wilm's tumour

(Science: oncology, tumour) wilm's tumour or nephroblastoma, is a cancerous tumour of the kidney in children.

Wilm's is the most common tumour of the kidney and the most common intra-abdominal tumour in children. The exact cause is unknown, but probably develops in foetal tissue due to an underlying genetic factor. Like retinoblastoma, both sporadic and inherited forms occur.

Believed to be caused by development of homozygosity for a deletion of the tip of the short arm of chromosome 11, which is presumed to contain a tumour suppressor gene.


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