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Wild type

Definition

noun

(1) The typical (or the most common) form, appearance or strain existing in the wild.

(2) The normal, non-mutated version of a gene common in nature.

(3) The allele at each locus required to produce the wild-type phenotype.


Supplement

The wild type is the most common form or phenotype in nature or in a natural breeding population.

In genetics, the wild-type organisms serve as the original parent strain before a deliberate mutation is introduced (for research) so that geneticists can use them as reference to compare the naturally occurring genotypes and phenotypes of a given species against those of the deliberately mutated counterparts.


Variant: wildtype (noun), wild-type (adjective)

Compare: mutant


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Results from our forum


Pyrosequencing

... orders and peak height ration will tell the prevalence of mutation in a wild type background.

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by kk
Tue Feb 12, 2013 2:42 pm
 
Forum: Molecular Biology
Topic: Pyrosequencing
Replies: 2
Views: 389

Knockout mice

If one parent is a wild-type mouse and the other is a homozygous knockout mouse, their offspring will be heterozygous at the knockout ...

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by jonmoulton
Tue Feb 05, 2013 5:29 pm
 
Forum: Genetics
Topic: Knockout mice
Replies: 5
Views: 674

Pyrosequencing

... when I reach a mutation hot spot, I add two dispensations - one for the wild type and one for the mutant nucleotide. Question1: how come that these hot spots always change ...

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by kk
Wed Jan 23, 2013 3:08 pm
 
Forum: Molecular Biology
Topic: Pyrosequencing
Replies: 2
Views: 389

Re: Muscular dystrophy inheritance question

... This suggests the female may be a carrier with a DMD allele and a wild-type allele for dystrophin, but the pedigree makes it look like she is expressing the DMD phenotype. ...

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by firefly
Wed Jan 09, 2013 9:16 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 1071

Re: Muscular dystrophy inheritance question

... This suggests the female may be a carrier with a DMD allele and a wild-type allele for dystrophin, but the pedigree makes it look like she is expressing the DMD phenotype. ...

See entire post
by jonmoulton
Wed Jan 09, 2013 5:06 pm
 
Forum: Molecular Biology
Topic: Muscular dystrophy inheritance question
Replies: 7
Views: 1071
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