
Dictionary » W » Wheal-and-flare reaction Wheal-and-flare reactionwheal-and-flare reaction --> wheal-and-erythema reaction The characteristic immediate reaction observed in the skin test; within 10 to 15 minutes after injection of antigen (allergen), an irregular, blanched, elevated wheal appears, surrounded by an area of erythema (flare). Synonym: wheal-and-flare reaction. ![]()
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