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West African sleeping sickness --> Gambian trypanosomiasis

A chronic disease of humans caused by trypanosoma brucei gambiense in northern and sub-Saharan Africa from senegal east to sudan and uganda; characterised by splenomegaly, drowsiness, an uncontrollable urge to sleep, and the development of psychotic changes; basal ganglia and cerebellar involvement commonly lead to chorea and athetosis; the terminal phase of the disease is characterised by wasting, anorexia, and emaciation that gradually leads to coma and death, usually from intercurrent infection.

Synonym: chronic African sleeping sickness, chronic trypanosomiasis, west African sleeping sickness, west African trypanosomiasis.