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Up mutation

up mutation

(Science: molecular biology) refers to any mutation in the promoter region of a gene which can trigger transcription initiation.

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CRISPR/Cas technology

It works well in mice. About off-targets: it's hyperbole . In mice unless the off target is in LD with your desired mutation, it can be bred out in 1-2 generations and even still, the off targets are primarily in intergenic noncoding sequence space ad exist in a homozygous state. ...

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by animodel123
Wed Mar 18, 2015 6:39 am
Forum: Genetics
Topic: CRISPR/Cas technology
Replies: 1
Views: 425


See: https://en.wikipedia.org/wiki/Polydactyly so 1) likely a mutation (or one of your parent was having a 6th finger and had it removed and for some reason chose not to tell or ignore it) 2) 50% chance of them having it 3) It would be stupid to do it ...

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by BrentElmer
Fri Jan 30, 2015 7:11 am
Forum: Genetics
Topic: 6 fingers
Replies: 5
Views: 5998

Mutuation saturation at a particular locus

Hi guys, newbie here, but no less enthusiastic! Quick question in regards to mutation saturation at a locus... What is it in the context of comparing two lineages? I know that it occurs most in hyper-variable regions like in mitDNA, but what effect does this have ...

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by SimonNSmith
Fri Dec 19, 2014 8:43 pm
Forum: Evolution
Topic: Mutuation saturation at a particular locus
Replies: 0
Views: 497

Evolutionary psychology

... I see that it is a possibility that such useless or harmful instincts prevail for some time, but it is also likely that such instincts may undergo mutation ( mutation in its broader sense) and selection to establish useful replacements. Longer the time since becoming not of use, more the chance ...

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by Hrushikesh
Thu Dec 04, 2014 8:58 pm
Forum: Evolution
Topic: Evolutionary psychology
Replies: 2
Views: 1967

translation from DNA

Even if that system would be more successful, could we have transitioned to it through gradual mutation and selection, or were we stuck with what we got?

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by wildfunguy
Tue Dec 02, 2014 11:23 pm
Forum: Molecular Biology
Topic: translation from DNA
Replies: 4
Views: 5396
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