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Dictionary » T » Tyrosine kinase

Tyrosine kinase

tyrosine kinase

(Science: enzyme) kinases that phosphorylate protein tyrosine residues. These kinases play major roles in mitogenic signalling and can be divided into two subfamilies: receptor tyrosine kinases, that have an extracellular ligand binding domain, a single transmembrane domain and an intracellular tyrosine kinase domain and nonreceptor tyrosine kinases, which are soluble, cytoplasmic kinases.

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Cell signalling inhibitors

... and tell me the enzyme or receptor that is inhibited? (Preferably for tyrosine kinase, G-protein, JAK/STAT and Phosphatidylinositol 3-kinase) Thanks :D

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by billyfisher100
Wed Jan 08, 2014 7:35 pm
Forum: Cell Biology
Topic: Cell signalling inhibitors
Replies: 1
Views: 577

Edman Degradation Problem

... some research on the internet I've come up with: serine, threonine, tyrosine, and histidine? Is this right? And as for the enzyme... either kinase or phosphatase? F) Again, I think I need the amino acid code for this, but I know that ...

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by pinkerpikachu
Sun Oct 16, 2011 7:35 pm
Forum: Molecular Biology
Topic: Edman Degradation Problem
Replies: 1
Views: 3304

insulin receptor substrate (IRS)

Is anybody familiar with the receptor tyrosine kinase (RTK) pathway. I am trying to figure out what the IRS compares to in the G-protein coupled receptor ...

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by hannahzarzar
Sun Sep 25, 2011 4:54 am
Forum: Cell Biology
Topic: insulin receptor substrate (IRS)
Replies: 1
Views: 1842

insulin pathways

... the blood to the alteration of the cell's metabolism. a) the receptor tyrosine kinase phosphorylates another receptor tyrosine kinase b)insulin binds extracellularly to the ...

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by nickname
Mon Nov 08, 2010 9:49 pm
Forum: Cell Biology
Topic: insulin pathways
Replies: 1
Views: 3394

Uncontrolled cell proliferation due to mutation

... D as well, because the phosphatases inactivate an active receptor tyrosine kinase by plucking of the phosphategroups, and if the phosphatases cannot recognize the receptor ...

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by Sophie33
Wed Oct 27, 2010 12:06 pm
Forum: Molecular Biology
Topic: Uncontrolled cell proliferation due to mutation
Replies: 6
Views: 6234
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