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Tube curare

Definition

noun

A curare from Chondodendron species and contains D-tubocurarine as its main toxin


Supplement

Curare refers to the toxic substance containing the alkaloid D-tubocurarine, and is used in making arrow heads. The substance is extracted from certain toxic plant species. It is a muscle relaxant that works by blocking the motor end plate transmission and by acting as a competitive antagonist for acetylcholine. It works by inhibiting the nicotinic acetylcholine receptor at the neuromuscular junction. When administered at a particular dose it can cause asphyxiation and subsequently death. According to Rudolf Boehm there are three common varieties of curare. Tube or bamboo curare is one of them; the other two are pot curate and gourd curare. Tube curare is named as such because of its packing into hollow tubes. The main toxin of this type of curare is d-tubocurarine. 1 The toxin d-tubocurarine is previously used as an adjunct for clinical anesthesia apart from making poisonous arrow heads.


Synonym(s):

  • bamboo curare

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Related term(s):


Reference(s):
1 Gray, TC (1947). "The Use of D-Tubocurarine Chloride in Anæsthesia". Ann R Coll Surg Engl 1 (4): 191–203. PMC 1940167.


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