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Truncated

truncated

1. Cut off; cut short; maimed.

2. (Science: chemical) Replaced, or cut off, by a plane, especially when equally inclined to the adjoining faces; as, a truncated edge.

3. (Science: zoology) Lacking the apex; said of certain spiral shells in which the apex naturally drops off.

(Science: geometry) Truncated cone or pyramid, a cone or pyramid whose vertex is cut off by a plane, the plane being usually parallel to the base.


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Re: How dominance works at the DNA/RNA/protein

... iniciation/polyA signal, whatever) leading to significantly reduced half-life of the mRNA. There may be STOP codon in middle of the gene yielding truncated protein. The protein may have mutated residue loosing all activity.

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by JackBean
Thu Oct 04, 2012 11:58 am
 
Forum: Genetics
Topic: How dominance works at the DNA/RNA/protein
Replies: 10
Views: 5936

DNA and Protein Synthesis

... will either completely impair the functioning of that protein or it won't be able to fold (and thus work). Lastly, you can get premature STOP and truncated protein. Question is, how premature the STOP codon would be, whether the fragment would be able of catalysis or not.

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by JackBean
Tue Feb 28, 2012 8:22 am
 
Forum: Genetics
Topic: DNA and Protein Synthesis
Replies: 2
Views: 4655

2 homologous chromosomes, both used for g.expression?

that depends, why is the allele recessive. Is it because the gene is truncated? Or is the protein just too low active? Or the promotor doesn't work?

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by JackBean
Fri Dec 30, 2011 10:36 pm
 
Forum: Genetics
Topic: 2 homologous chromosomes, both used for g.expression?
Replies: 3
Views: 1296

Question about site-directed mutation

... did not work. Primers are not good? Probably but maybe not . I use the same PCR system and different annealing temperature to amplify my protein truncated using Protein_F and mutant_R. It work!!!at different annealing temp. form 40-60 oC Which showed that the mutation primers can bind template. ...

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by flyflycat
Mon Nov 22, 2010 8:02 pm
 
Forum: Molecular Biology
Topic: Question about site-directed mutation
Replies: 1
Views: 725

Re: Capping termini - protein modeling

... to phrase the question...what is the best way to treat terminal residues in protein modelling and MD. The residues are not the end of sequence but truncated, as obtained from the crystal structure. Such terminal residues in my case include...Thr, Ser, Glu, Gln, Val. Should I have these residues ...

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by CoffeeIsTheColour
Fri Sep 10, 2010 3:15 pm
 
Forum: Bioinformatics
Topic: Capping termini - protein modeling
Replies: 2
Views: 2891
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