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Troponin i

Definition

noun

One of the three polypeptides that make up the troponin complex. It binds to actin in thin filament, holding the troponin-tropomyosin complex in place.


Supplement

Troponin is a complex made up of three regulatory proteins:


Word origin: from the complex troponin and I for its inhibitory character


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Evolution on the molecular level

... of muscle contraction, the action potential causing a release of Calcium from the SR, followed by the "turning off" of tropomyosin by troponin to expose the active sites on the myosin heads so that they can bind to the actin and initiate contraction, then you know what an incredible ...

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by rogcha22
Fri Feb 22, 2008 10:37 pm
 
Forum: Evolution
Topic: Evolution on the molecular level
Replies: 5
Views: 1460

troponin

Troponin is a serum cardiac marker that is released into the blood in large quantities from the necrotic heart muscle after a heart attack. It is a very good indicator because it remains elevated two weeks after the initial ...

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by bionewbie
Thu Apr 12, 2007 1:14 am
 
Forum: Human Biology
Topic: troponin
Replies: 2
Views: 802

troponin

Didn't realize they were using troponin to monitor heart damage. The traditional monitors were enzymes like SGOT--to name one. When there is tissue damage due to heart attack or cirrhosis of the liver, these enzymes leak out of the dead ...

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by blcr11
Tue Apr 10, 2007 5:56 pm
 
Forum: Human Biology
Topic: troponin
Replies: 2
Views: 802

troponin

Hey there WHY is elevated levels of troponin good indicators of heart damage...ive tried online/textbook but the only thing it syas is that elevated levels of troponin are good indicators but not WHY?...does it have somehting to do with the ...

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by biology_06er
Tue Apr 10, 2007 2:54 am
 
Forum: Human Biology
Topic: troponin
Replies: 2
Views: 802

Calcium regulated muscle cell contraction

... is available. It's true, though, that a deficit in ATP will cause muscle stiffness because in the ADP-form the myosinheads cant release from the troponin, which is Ca(2+) dependant in making a bindingsite for myosin. (in rigor mortis Ca(2+) will diffuse out of the ER but no ATP is available leading ...

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by sdekivit
Sat May 06, 2006 10:34 am
 
Forum: Cell Biology
Topic: Calcium regulated muscle cell contraction
Replies: 1
Views: 827
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