Dictionary » T » Trinucleotide repeat expansion disorder

Trinucleotide repeat expansion disorder

Definition

noun, plural: trinucleotide repeat disorders

Any of a set of genetic disorders caused by trinucleotide repeats exceeding the stable threshold and expanding in successive generations (thus resulting in a non-Mendelian inheritance pattern).


Supplement

Many of the trinucleotide repeat expansion disorders show neurological or cognitive symptoms. Fragile X syndrome, Huntington disease, myotonic dystrophy, and Machado-Joseph disease are examples of trinucleotide expansion repeat disorders.


Also called:

Mentioned in:


Please contribute to this project, if you have more information about this term feel free to edit this page



This page was last modified 00:35, 20 August 2010. This page has been accessed 460 times. 
What links here | Related changes | Permanent link