Dictionary » T » Transversion



noun, plural: transversions

(genetics) A base-pair substitution mutation in which a purine is replaced by pyrimidine (e.g. A → C), and vice versa (e.g. T → G)


In terms of functionality this mutation can lead to a missense mutation. Transversions can be caused by ionizing radiation and alkylating agents.

To view a study on thymine to guanine transversion, view this article.

Compare: transition (genetics)
See also: substitution mutation

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reversion of transitions and transversion

Does anyone encounter the general theory explaining the frequency of reversion for transitions and transversion? I’m trying to figure out what could be the probability of reversion for C->T transition that I’ve introduced to one of my constructs. I would appreciate any ...

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Thu Jan 22, 2009 4:06 am
Forum: Molecular Biology
Topic: reversion of transitions and transversion
Replies: 0
Views: 971

The Fiber Disease

... dataset was used to empirically determine nucleotide frequencies and instantaneous substitution rates with the restriction of a 2:1 transition to transversion ratio. The organisms used in our tree and the accession numbers for their small subunit rRNA sequences include Artemia salina (X01723), ...

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by al
Mon Dec 25, 2006 1:39 am
Forum: Human Biology
Topic: The Fiber Disease
Replies: 7403
Views: 6245391

repair mechanism?

The result depends on the kind of correction the repair mechanism is suppose to correct: transition, transversion, nick, and many other possibilities.

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by canalon
Fri Nov 10, 2006 11:36 pm
Forum: Genetics
Topic: repair mechanism?
Replies: 8
Views: 4994

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