noun, plural: transversions

(genetics) A base-pair substitution mutation in which a purine is replaced by pyrimidine (e.g. A → C), and vice versa (e.g. T → G)


In terms of functionality this mutation can lead to a missense mutation. Transversions can be caused by ionizing radiation and alkylating agents.

To view a study on thymine to guanine transversion, view this article.

Compare: transition (genetics)
See also: substitution mutation

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