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Transposase

transposase --> transposon

(Science: molecular biology) small, mobile dNA sequences that can replicate and insert copies at random sites within chromosomes. They have nearly identical sequences at each end, oppositely oriented (inverted) repeats and code for the enzyme, transposase, that catalyses their insertion.

bacteria have two types of transposon, simple transposons that have only the genes needed for insertion and complex transposons that contain genes in addition to those needed for insertion.

eukaryotes contain two classes of mobile genetic elements, the first are like bacterial transposons in that dNA sequences move directly. The second class (retrotransposons) move by producing rNA that is transcribed, by reverse transcriptase, into dNA which is then inserted at a new site.


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Viral DNA in Host DNA?

Look up transposase and integrase.

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by Cat
Sat Nov 24, 2012 4:31 pm
 
Forum: Genetics
Topic: Viral DNA in Host DNA?
Replies: 1
Views: 988

Re: no repeat sequences in exons of genes?

... although such proteins-coding sequences are often a mess due to mutations - for jumping the gene only needs to have jumping signals to jump - the transposase can be provided by say a viral infection or another transposon which ironically may have mutations in its jump-signal DNA which mean it ...

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by merv
Mon Oct 03, 2011 1:37 am
 
Forum: Genetics
Topic: no repeat sequences in exons of genes?
Replies: 5
Views: 10418

Insertional Sequences

Hi All Do ISes have promoter? If no, how do they manage to get their transposase transcribed? By chance alone?

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by cnite
Sun May 11, 2008 4:04 pm
 
Forum: Molecular Biology
Topic: Insertional Sequences
Replies: 4
Views: 1519

transposase and recombination

Site specific DNA recombination involves recombinase. Transposase is not specific enough.

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by Cat
Thu Mar 27, 2008 5:15 pm
 
Forum: Genetics
Topic: transposase and recombination
Replies: 1
Views: 1471

transposase and recombination

Can a transposase be involved in site specific DNA recombination?

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by pervypirate
Thu Mar 27, 2008 4:48 pm
 
Forum: Genetics
Topic: transposase and recombination
Replies: 1
Views: 1471
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