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Dictionary » T » Transmembrane protein

Transmembrane protein

Definition

noun, plural: transmembrane proteins

A protein that spans the entire biological membrane.


Supplement

Transmembrane proteins may be classified in two major groups:


Word origin: L, comb. form of trāns (adv. and prep.) across, beyond, through + -membrane.

Acronym: TM.

See also: porin, ion channel.


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Beet Cell Damage

... to consider. First, the acid/base treatment is likely to denature proteins and disrupt membrane integrity. Second, chloroform extraction will separate the lipids from the membrane leaving the proteins behind. But transmembrane proteins generally have very hydrophobic trans- or inter-membrane ...

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by blcr11
Tue Dec 09, 2008 2:09 pm
 
Forum: Cell Biology
Topic: Beet Cell Damage
Replies: 2
Views: 924

Re: X Ray crystallography & transmembrane proteins

The crystallization of membrane proteins in toto is one of the “holy grails” of crystallography. There is no general ... few cases that have succeeded, two (rhodopsin and F1-ATPase) won Nobel Prizes. Transmembrane regions of membrane and integral membrane proteins tend to be very hydrophobic. ...

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by blcr11
Fri Sep 05, 2008 11:43 am
 
Forum: Molecular Biology
Topic: X Ray crystallography & transmembrane proteins
Replies: 5
Views: 704

Re: lateral movement of proteins in lipid bilayer

... "traverse the plane of the membrane" refers to the ability of transmembrane proteins to move about side-to-side in the membrane without leaving the membrane. One reason ...

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by jonmoulton
Mon Aug 04, 2008 5:22 pm
 
Forum: Cell Biology
Topic: lateral movement of proteins in lipid bilayer
Replies: 4
Views: 1517

Multiple choice questions

... hoping someone could give me an answear. 1. Hydrophobic interaction in protein is giving important stabilization contributions a) to proteins secundary- ... carbohydrate groups on the cytoplasmatic side d) have a hydrophobic transmembrane domain e) constitue about 10% of the membrane proteins Small ...

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by Luna
Sun Feb 24, 2008 9:48 pm
 
Forum: Molecular Biology
Topic: Multiple choice questions
Replies: 2
Views: 1696

Gene activation?

... are two scenarios: Scenario 1: Gene X cause cells to divide when the protein it codes for is active. If the gene mutates in such a way that the ... active, the cell can turn cancerous. (An example of this is the c-kit transmembrane protein in mast cells causing mastocytosis). Scenario 2: Gene ...

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by BioLad
Thu Feb 14, 2008 5:30 pm
 
Forum: Genetics
Topic: Gene activation?
Replies: 2
Views: 686
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