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Transgenic mice

transgenic mice

mice that have a piece of foreign lincor dNA integrated into their genome.

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How to stimulate hepatocyte proliferation in vivo

... pregnancy, liver size and weight will be increase about 50% in female mice. If you want to use a nature method, you can try this one, but only ... http://www.creative-animodel.com/Animal-Model-Development/Transgenic-Animals.htm l, if you have any need in transgenic mouse research.

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by animodel123
Wed Mar 18, 2015 6:55 am
Forum: Genetics
Topic: How to stimulate hepatocyte proliferation in vivo
Replies: 1
Views: 1519

An Overview of Embryonic Stem Cells

... technology used to produce hundreds of ‘knock out’ and ‘knock in’ transgenic animals for the investigation of gene expression and regulation ... involves reconstitution of embryos and the generation of chimaeric mice, however, for human cells this test cannot be applied for obvious reasons. ...

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by 2444256703
Thu Jan 29, 2015 6:48 am
Forum: Cell Biology
Topic: An Overview of Embryonic Stem Cells
Replies: 0
Views: 667

Conditional knockout mouse

Hello, I am using transgenic mouse where my gene of interest is floxed. When I cross this mouse line with Tamoxifen inducible Cre line, CAGGCre-ERTM, I get mice with with heterozygous Cre and floxed gene of interest. The experimental plan was to isolate ...

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by aji01
Wed Feb 20, 2013 11:25 am
Forum: Genetics
Topic: Conditional knockout mouse
Replies: 1
Views: 2078

question about LCM

... I am set to perform LCM on PFA-fixed midbrain sections of TH-GPF transgenic mice and encountered some problems. The quantity and quality of RNA isolated from LCM cells ...

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by johnmay
Mon Oct 17, 2011 4:43 pm
Forum: Molecular Biology
Topic: question about LCM
Replies: 0
Views: 1579

Problem with transgenic mice

I have sent purified plasmid DNA to mouse transgenic core to develop transgenic mice with that specific DNA piece. Out of about 45 mice that I genotyped, only about 3 mice gave me ...

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by ougadougou
Fri Sep 30, 2011 3:04 am
Forum: Genetics
Topic: Problem with transgenic mice
Replies: 2
Views: 8027
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