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Transcription factor

transcription factor

(Science: molecular biology) protein required for recognition by rNA polymerases of specific stimulatory sequences in eukaryotic genes.

Several are known that activate transcription by rNA polymerase II when bound to upstream promoters.

transcription of the 5S rNA gene in xenopus by rNA polymerase III is dependent on a 40 kD protein TFIIIA that binds to a regulatory site in the centre of the gene and was the first protein found to exhibit the metal binding domains known as zinc fingers.


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Comprehensive List of TFBSs database from ChIP-Seq data

Comprehensive List of transcription factor binding sites (TFBSs) databases based on ChIP-seq data as follows: (1) ChEA : transcription factor ...

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by rnaworld2110
Fri Feb 15, 2013 6:59 am
 
Forum: Molecular Biology
Topic: Comprehensive List of TFBSs database from ChIP-Seq data
Replies: 0
Views: 224

p53 question

PHF20 is a transcription factor that seems to be unique to the production of p53. (see http://www.sciencedaily.com/releases/2012/08/120824082534.htm ...

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by qwerter
Wed Feb 13, 2013 2:07 am
 
Forum: Cell Biology
Topic: p53 question
Replies: 1
Views: 272

Molecular bio questions

Hi i need help with these two questions. 1, Gal 4 is a yeast transcription factor that binds to a specific DNA sequence referred to as UAS and it promotes RNA synthesis: ...

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by revision
Sun Nov 25, 2012 4:16 pm
 
Forum: Molecular Biology
Topic: Molecular bio questions
Replies: 2
Views: 513

Re: Comprehensive List of microRNA target databases and software

new miRNA target database. (1) ChIPBase , decoding the post-transcriptional and transcriptional regulation of microRNAs from CLIP-Seq and ChIP-Seq data. It constructed TF(transcription factor)->microRNA->targets regulatory networks. (2) doRiNA : a database of RNA ...

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by rnaworld2110
Mon Nov 19, 2012 4:41 pm
 
Forum: Molecular Biology
Topic: Comprehensive List of microRNA target databases and software
Replies: 3
Views: 4993

Direct or indirect protein-DNA interaction

Greetings, How would one go about deducing whether a certain DNA binding transcription factor has a direct interaction with a gene of interest ( we know that the TF has impact on ...

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by nukeman
Wed Oct 31, 2012 5:21 pm
 
Forum: Molecular Biology
Topic: Direct or indirect protein-DNA interaction
Replies: 1
Views: 356
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