(Science: chemical) A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.

Pharmacological action: adrenergic alpha-antagonists, antihypertensive agents, sympatholytics, vasodilator agents.

Chemical name: 1H-imidazole, 4,5-dihydro-2-(phenylmethyl)-

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