Thymus

... .2 are described in Shiku et al . (ref. 10, Table III) . The Ly antisera we used, diluted 1 :10, were absorbed once with 120 x 10 8 syngeneic thymus + LNC/ml to remove autoantibody . Complement (C)-Dependent Cytotoxicity Assay . 10-40 x 10 8 cells/ml ("Cr-labeled ; 30 min, 100 juCi/ml) ...

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... are usually defined by the structure of the receptor, and with T cells the arrangement of alpha and beta chains whilst they mature in the thymus, therefore they will need very little of one cytokine to have an effect and a much higher concentration of another. This affinity regulation ...

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So even if a virus could invade the thymus and thus eliminate the T cells specific for it, the somewhat loose nature of TCR binding would allow other T cells with near-identical TCRs to recognize the virus. Interesting... But if this loose ...

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So even if a virus could invade the thymus and thus eliminate the T cells specific for it, the somewhat loose nature of TCR binding would allow other T cells with near-identical TCRs to recognize the virus. Interesting... But if this loose ...

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... said that many clonal TCRs can recognize several epitopes with varying affinities - with varying outcomes. So even if a virus could invade the thymus and thus eliminate the T cells specific for it, the somewhat loose nature of TCR binding would allow other T cells with near-identical TCRs to ...

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