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Thromboxane a2

thromboxane a2

(Science: chemical) An unstable intermediate between the prostaglandin endoperoxides and thromboxane b2. The compound has a bicyclic oxaneoxetane structure. It is a potent inducer of platelet aggregation and causes vasoconstriction. It is the principal component of rabbit aorta contracting substance (rcs).

Chemical name: Thromboxa-5,13-dien-1-oic acid, 9,11-epoxy-15-hydroxy-, (5Z,9alpha,11alpha,13E,15S)-


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Cardiovascular disease (CVD)

... When blood comes into contact with fatty and fibrous tissue, platelets stick to the roughened surface and release clotting factors called thromboxanes. In healthy arteries the amount of thromboxane and prostaglandin is balanced, but in damaged arteries the balance is upset because the ...

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by sharleenreyna
Wed Apr 20, 2011 9:48 am
 
Forum: General Discussion
Topic: Cardiovascular disease (CVD)
Replies: 5
Views: 10068


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